ID   BSSR_ECO57              Reviewed;         127 AA.
AC   P0AAY2; P75803;
DT   11-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2005, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=Biofilm regulator BssR;
GN   Name=bssR; OrderedLocusNames=Z1062, ECs0916;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA   Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA   Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA   Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA   Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA   Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA   Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA   Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT   genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- FUNCTION: Represses biofilm formation in M9C glu and LB glu media but
CC       not in M9C and LB media. Seems to act as a global regulator of several
CC       genes involved in catabolite repression and stress response and
CC       regulation of the uptake and export of signaling pathways. Could be
CC       involved the regulation of indole as well as uptake and export of AI-2
CC       through a cAMP-dependent pathway (By similarity). {ECO:0000250}.
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DR   EMBL; AE005174; AAG55212.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB34339.1; -; Genomic_DNA.
DR   PIR; D90743; D90743.
DR   PIR; H85593; H85593.
DR   RefSeq; NP_308943.1; NC_002695.1.
DR   RefSeq; WP_000497137.1; NZ_SWKA01000005.1.
DR   AlphaFoldDB; P0AAY2; -.
DR   STRING; 155864.EDL933_0963; -.
DR   EnsemblBacteria; AAG55212; AAG55212; Z1062.
DR   EnsemblBacteria; BAB34339; BAB34339; ECs_0916.
DR   GeneID; 66670890; -.
DR   GeneID; 917658; -.
DR   KEGG; ece:Z1062; -.
DR   KEGG; ecs:ECs_0916; -.
DR   PATRIC; fig|386585.9.peg.1032; -.
DR   eggNOG; ENOG5030IAT; Bacteria.
DR   HOGENOM; CLU_161265_0_0_6; -.
DR   OMA; NDHLRDN; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   InterPro; IPR020359; Biofilm_regulator_BssR.
DR   Pfam; PF10799; YliH; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..127
FT                   /note="Biofilm regulator BssR"
FT                   /id="PRO_0000168733"
SQ   SEQUENCE   127 AA;  14536 MW;  F7BFD58CA74BC472 CRC64;
     MFVDRQRIDL LNRLIDARVD LAAYVQLRKA KGYMSVSESN HLRDNFFKLN RELHDKSLRL
     NLHLDQEEWS ALHHAEEALA TAAVCLMSGH HDCPTVITVN ADKLENCLMS LTLSIQSLQK
     HAMLEKA