ID   TLXNB_HUMAN             Reviewed;         122 AA.
AC   P0CAT3;
DT   16-JUN-2009, integrated into UniProtKB/Swiss-Prot.
DT   16-JUN-2009, sequence version 1.
DT   25-MAY-2022, entry version 51.
DE   RecName: Full=Putative TLX1 neighbor protein;
DE   AltName: Full=TLX1 divergent gene protein;
GN   Name=TLX1NB; Synonyms=TDI;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15164054; DOI=10.1038/nature02462;
RA   Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L.,
RA   Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K.,
RA   Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L.,
RA   Taylor A., Battles J., Bird C.P., Ainscough R., Almeida J.P.,
RA   Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J.,
RA   Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., Brown J.Y.,
RA   Burford D.C., Burrill W., Burton J., Cahill P., Camire D., Carter N.P.,
RA   Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., Corby N.,
RA   Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., Frankish A.,
RA   Frankland J.A., Garner P., Garnett J., Gribble S., Griffiths C.,
RA   Grocock R., Gustafson E., Hammond S., Harley J.L., Hart E., Heath P.D.,
RA   Ho T.P., Hopkins B., Horne J., Howden P.J., Huckle E., Hynds C.,
RA   Johnson C., Johnson D., Kana A., Kay M., Kimberley A.M., Kershaw J.K.,
RA   Kokkinaki M., Laird G.K., Lawlor S., Lee H.M., Leongamornlert D.A.,
RA   Laird G., Lloyd C., Lloyd D.M., Loveland J., Lovell J., McLaren S.,
RA   McLay K.E., McMurray A., Mashreghi-Mohammadi M., Matthews L., Milne S.,
RA   Nickerson T., Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V.,
RA   Peck A.I., Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A.,
RA   Ross M.T., Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M.,
RA   Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., Tracey A.,
RA   Tromans A., Tsolas J., Wall M., Walsh J., Wang H., Weinstock K., West A.P.,
RA   Willey D.L., Whitehead S.L., Wilming L., Wray P.W., Young L., Chen Y.,
RA   Lovering R.C., Moschonas N.K., Siebert R., Fechtel K., Bentley D.,
RA   Durbin R.M., Hubbard T., Doucette-Stamm L., Beck S., Smith D.R., Rogers J.;
RT   "The DNA sequence and comparative analysis of human chromosome 10.";
RL   Nature 429:375-381(2004).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [3]
RP   IDENTIFICATION.
RX   PubMed=17303350; DOI=10.1016/j.gene.2006.12.034;
RA   Greene W.K., Sontani Y., Sharp M.A., Dunn D.S., Kees U.R., Bellgard M.I.;
RT   "A promoter with bidirectional activity is located between TLX1/HOX11 and a
RT   divergently transcribed novel human gene.";
RL   Gene 391:223-232(2007).
CC   -!- MISCELLANEOUS: Oriented in a head-to-head manner with TLX1/HOX11. Both
CC       genes share the same promoter with robust bidirectional activity.
CC   -!- CAUTION: Product of a dubious CDS prediction. {ECO:0000305}.
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DR   EMBL; AL133215; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BC019674; -; NOT_ANNOTATED_CDS; mRNA.
DR   AlphaFoldDB; P0CAT3; -.
DR   SMR; P0CAT3; -.
DR   STRING; 9606.ENSP00000475001; -.
DR   BioMuta; HGNC:37183; -.
DR   PRIDE; P0CAT3; -.
DR   UCSC; uc001ksv.4; human.
DR   GeneCards; TLX1NB; -.
DR   HGNC; HGNC:37183; TLX1NB.
DR   MIM; 612734; gene.
DR   neXtProt; NX_P0CAT3; -.
DR   PharmGKB; PA165549107; -.
DR   eggNOG; ENOG502R9W5; Eukaryota.
DR   ChiTaRS; TLX1NB; human.
DR   Pharos; P0CAT3; Tdark.
DR   Proteomes; UP000005640; Unplaced.
DR   RNAct; P0CAT3; protein.
PE   5: Uncertain;
KW   Reference proteome.
FT   CHAIN           1..122
FT                   /note="Putative TLX1 neighbor protein"
FT                   /id="PRO_0000378336"
FT   REGION          21..122
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   122 AA;  13375 MW;  65819A31A9996D7C CRC64;
     MAPLQLLHPW GRRGAWASQH SLLSQEAMGP GEGAEPTPWG YLRAEHWGAS PSGAPTLPFA
     PDECSLTPGS PPHPLNKQKH HPPHPSQTQK DLVPRSPQLE KSRIRLRRTL RNLGGGRGQR
     GQ