ID   BSSR_SHIFL              Reviewed;         127 AA.
AC   P0AAY3; P75803;
DT   11-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2005, sequence version 1.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=Biofilm regulator BssR;
GN   Name=bssR; OrderedLocusNames=SF0786, S0829;
OS   Shigella flexneri.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=623;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=301 / Serotype 2a;
RX   PubMed=12384590; DOI=10.1093/nar/gkf566;
RA   Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA   Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA   Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA   Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT   "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT   through comparison with genomes of Escherichia coli K12 and O157.";
RL   Nucleic Acids Res. 30:4432-4441(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX   PubMed=12704152; DOI=10.1128/iai.71.5.2775-2786.2003;
RA   Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G.,
RA   Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T.,
RA   Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.;
RT   "Complete genome sequence and comparative genomics of Shigella flexneri
RT   serotype 2a strain 2457T.";
RL   Infect. Immun. 71:2775-2786(2003).
CC   -!- FUNCTION: Represses biofilm formation in M9C glu and LB glu media but
CC       not in M9C and LB media. Seems to act as a global regulator of several
CC       genes involved in catabolite repression and stress response and
CC       regulation of the uptake and export of signaling pathways. Could be
CC       involved the regulation of indole as well as uptake and export of AI-2
CC       through a cAMP-dependent pathway (By similarity). {ECO:0000250}.
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DR   EMBL; AE005674; AAN42419.1; -; Genomic_DNA.
DR   EMBL; AE014073; AAP16295.1; -; Genomic_DNA.
DR   RefSeq; NP_706712.1; NC_004337.2.
DR   RefSeq; WP_000497137.1; NZ_WPGW01000151.1.
DR   AlphaFoldDB; P0AAY3; -.
DR   STRING; 198214.SF0786; -.
DR   EnsemblBacteria; AAN42419; AAN42419; SF0786.
DR   EnsemblBacteria; AAP16295; AAP16295; S0829.
DR   GeneID; 1023773; -.
DR   GeneID; 66670890; -.
DR   KEGG; sfl:SF0786; -.
DR   KEGG; sfx:S0829; -.
DR   PATRIC; fig|198214.7.peg.912; -.
DR   HOGENOM; CLU_161265_0_0_6; -.
DR   OMA; NDHLRDN; -.
DR   OrthoDB; 1774173at2; -.
DR   Proteomes; UP000001006; Chromosome.
DR   Proteomes; UP000002673; Chromosome.
DR   InterPro; IPR020359; Biofilm_regulator_BssR.
DR   Pfam; PF10799; YliH; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..127
FT                   /note="Biofilm regulator BssR"
FT                   /id="PRO_0000168734"
SQ   SEQUENCE   127 AA;  14536 MW;  F7BFD58CA74BC472 CRC64;
     MFVDRQRIDL LNRLIDARVD LAAYVQLRKA KGYMSVSESN HLRDNFFKLN RELHDKSLRL
     NLHLDQEEWS ALHHAEEALA TAAVCLMSGH HDCPTVITVN ADKLENCLMS LTLSIQSLQK
     HAMLEKA