ID   TM104_CHICK             Reviewed;         497 AA.
AC   Q5F3I6;
DT   31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 64.
DE   RecName: Full=Transmembrane protein 104;
GN   Name=TMEM104; ORFNames=RCJMB04_15p16;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB; TISSUE=Bursa of Fabricius;
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TMEM104 family. {ECO:0000305}.
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DR   EMBL; AJ851664; CAH65298.1; -; mRNA.
DR   RefSeq; NP_001026278.1; NM_001031107.1.
DR   AlphaFoldDB; Q5F3I6; -.
DR   STRING; 9031.ENSGALP00000012546; -.
DR   PaxDb; Q5F3I6; -.
DR   PRIDE; Q5F3I6; -.
DR   GeneID; 422110; -.
DR   KEGG; gga:422110; -.
DR   CTD; 54868; -.
DR   VEuPathDB; HostDB:geneid_422110; -.
DR   eggNOG; KOG3832; Eukaryota.
DR   InParanoid; Q5F3I6; -.
DR   PhylomeDB; Q5F3I6; -.
DR   PRO; PR:Q5F3I6; -.
DR   Proteomes; UP000000539; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR013057; AA_transpt_TM.
DR   Pfam; PF01490; Aa_trans; 2.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..497
FT                   /note="Transmembrane protein 104"
FT                   /id="PRO_0000254181"
FT   TOPO_DOM        1..10
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        11..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        32..35
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        36..56
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        57..148
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        149..169
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        170..205
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        206..226
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        227..234
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        235..255
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        256..277
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        278..298
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        299..306
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        307..327
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        328..356
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        357..377
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        378..398
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        399..419
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        420..421
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        422..442
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        443..471
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        472..492
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        493..497
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        194
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   497 AA;  56119 MW;  90E012B47BC9E40B CRC64;
     MAGGITDTGE LYSPYVGLVY MFNLIVGTGA LTMPKAFATA GWLVSLVLLM FLGFMSYMTT
     TFVVEAMAAA NAQLRWKRME KRKEDDEDED SSSGVSDSDV LLRDSYERAE TRPILSVQRR
     GSPNIFEITE RVEMGQMASM FFNKVGVNLF YFCIIIYLYG DLAIYAAAVP VSLMQVTCAI
     GNHSCNVGDG TKYNDTDKCW GPIRRIDAYR LYLAAFTLLL GPFTFFNVQK TKYLQIMTSL
     MRWIAFILMI ILALIRISRG QAEGHPSMAQ LSGIRNLFGV CVYSFMCQHS LPSLITPISK
     KRHVNKLVLL DYILILAFYS LLSFTAIYCF RNDTLMDMYT LNFTNCEIIN VAFIRYFLGL
     FPVFTISTNF PIIAVTLRNN WKTLFHREGG TYPWLVDRIV FPAITLVPPV LVVFCTHDLE
     SLVGITGAYA GNGIQYLIPA FLAYCSRKDT QLVFGSGTVN KHLSPFRHTF WIVFVLIWGF
     SCFVFVTANI VLSESKL