ID   TM104_DICDI             Reviewed;         499 AA.
AC   Q54S12;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=Transmembrane protein 104 homolog;
GN   Name=tmem104; ORFNames=DDB_G0282723;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TMEM104 family. {ECO:0000305}.
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DR   EMBL; AAFI02000047; EAL66221.1; -; Genomic_DNA.
DR   RefSeq; XP_640227.1; XM_635135.1.
DR   AlphaFoldDB; Q54S12; -.
DR   PaxDb; Q54S12; -.
DR   EnsemblProtists; EAL66221; EAL66221; DDB_G0282723.
DR   GeneID; 8623767; -.
DR   KEGG; ddi:DDB_G0282723; -.
DR   dictyBase; DDB_G0282723; tmem104.
DR   eggNOG; KOG3832; Eukaryota.
DR   HOGENOM; CLU_025541_1_0_1; -.
DR   InParanoid; Q54S12; -.
DR   OMA; DVVCDQT; -.
DR   PhylomeDB; Q54S12; -.
DR   PRO; PR:Q54S12; -.
DR   Proteomes; UP000002195; Chromosome 3.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR013057; AA_transpt_TM.
DR   Pfam; PF01490; Aa_trans; 1.
PE   3: Inferred from homology;
KW   Glycoprotein; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..499
FT                   /note="Transmembrane protein 104 homolog"
FT                   /id="PRO_0000330343"
FT   TRANSMEM        16..36
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        39..59
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        158..178
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        197..217
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        234..254
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        257..277
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        303..323
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        363..383
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        402..422
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        428..448
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        476..496
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        97
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        184
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        351
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        424
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   499 AA;  55471 MW;  86729ECDA149B8DF CRC64;
     MAGGPSDGST YSKKTAFVYI FNLIVGVGAL ALPYGFSKAG LVLGLLFLAA IGFLAFITAT
     WLIEGLSIAN FILVNKKEER IIGDDDNENY QKPPTENDSL INSEYSDNKI LQSNAEDRNL
     LEPSGGSSSS DNEQFEIKKR VEVGEMSKMF LGNIGYKVFY GVLIIYLFGD LSIYAATVPT
     TLANVTGGWG KFTDHTVYYF YLFLFACFVG PFSLFNFQKT KYLQFATLIT RNVAFLLMII
     LSIIFIAQGN GASIKQVPIF EISELASIFG VSIYSFMTHH SIPGFLTPIS KKDRLFTLMG
     LDFILVFIAY GTLCVVSLFA FGAVTNPTCA TASTSIHTFI PCQIQSLYIY NFTSYNSKFV
     SDFLSLFPVF TLSTNYILIS ITLRNNLLQL ITWKQDKISS KVRNVVFSLT SSLIPVGVAF
     CTRNVSLLVN ITGSYAGLGI MFVMPALISF YSNKILIEQY HISNPKKSPF SNKFFYLLIL
     LISVICLILA TWKIIITYK