TM107_DANRE
ID TM107_DANRE Reviewed; 135 AA.
AC Q6NZZ4;
DT 31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 82.
DE RecName: Full=Transmembrane protein 107;
GN Name=tmem107; ORFNames=zgc:77926;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May play a role in cilia formation and embryonic patterning.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
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DR EMBL; BC065897; AAH65897.1; -; mRNA.
DR RefSeq; NP_998376.1; NM_213211.1.
DR AlphaFoldDB; Q6NZZ4; -.
DR Ensembl; ENSDART00000170410; ENSDARP00000137423; ENSDARG00000059150.
DR GeneID; 406492; -.
DR KEGG; dre:406492; -.
DR CTD; 84314; -.
DR ZFIN; ZDB-GENE-040426-2294; tmem107.
DR GeneTree; ENSGT00390000014827; -.
DR HOGENOM; CLU_127745_0_0_1; -.
DR InParanoid; Q6NZZ4; -.
DR OMA; FQQWECW; -.
DR OrthoDB; 1508335at2759; -.
DR PhylomeDB; Q6NZZ4; -.
DR PRO; PR:Q6NZZ4; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Chromosome 14.
DR Bgee; ENSDARG00000059150; Expressed in mature ovarian follicle and 25 other tissues.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0036038; C:MKS complex; IBA:GO_Central.
DR GO; GO:1905515; P:non-motile cilium assembly; IBA:GO_Central.
DR GO; GO:1904491; P:protein localization to ciliary transition zone; IBA:GO_Central.
DR InterPro; IPR029248; TMEM107.
DR PANTHER; PTHR34341; PTHR34341; 1.
DR Pfam; PF14995; TMEM107; 1.
PE 2: Evidence at transcript level;
KW Cilium biogenesis/degradation; Developmental protein; Membrane;
KW Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..135
FT /note="Transmembrane protein 107"
FT /id="PRO_0000254544"
FT TRANSMEM 7..27
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 55..75
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 83..103
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 110..130
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 135 AA; 15312 MW; 78BF2ED8CBFD22DC CRC64;
MSALKSLVPA RFLTLTAHLV IIITIFWSRD NNIQSCLPLE FTEDQYRTED TRLTVALSVT
LALFVLELAG FLSGVSMFNS NQALLSLITH SSACVCLSFF VFHQWPCWTY WIIFSICSVF
PAVVELFLLL SQRVL