TM11A_XENLA
ID TM11A_XENLA Reviewed; 187 AA.
AC A2BD92;
DT 05-APR-2011, integrated into UniProtKB/Swiss-Prot.
DT 20-FEB-2007, sequence version 1.
DT 03-AUG-2022, entry version 33.
DE RecName: Full=Transmembrane protein 11-A, mitochondrial;
GN Name=tmem11-a; Synonyms=tmem11;
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Liver;
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Plays a role in mitochondrial morphogenesis. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC Multi-pass membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the TMEM11 family. {ECO:0000305}.
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DR EMBL; BC130106; AAI30107.1; -; mRNA.
DR RefSeq; NP_001091267.1; NM_001097798.1.
DR AlphaFoldDB; A2BD92; -.
DR DNASU; 100037074; -.
DR GeneID; 100037074; -.
DR KEGG; xla:100037074; -.
DR CTD; 100037074; -.
DR Xenbase; XB-GENE-961895; tmem11.L.
DR OMA; CCKYQLE; -.
DR OrthoDB; 1222072at2759; -.
DR Proteomes; UP000186698; Chromosome 9_10L.
DR Bgee; 100037074; Expressed in oocyte and 19 other tissues.
DR GO; GO:0031305; C:integral component of mitochondrial inner membrane; ISS:UniProtKB.
DR GO; GO:0007005; P:mitochondrion organization; ISS:UniProtKB.
DR InterPro; IPR026120; TMEM11.
DR PANTHER; PTHR15099; PTHR15099; 1.
DR Pfam; PF14972; Mito_morph_reg; 1.
PE 2: Evidence at transcript level;
KW Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..187
FT /note="Transmembrane protein 11-A, mitochondrial"
FT /id="PRO_0000406211"
FT TRANSMEM 79..95
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 102..119
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 187 AA; 21037 MW; 30E81D627EDAA760 CRC64;
MATWGRRRAG LGGRERVTLS AGECYIVHEI YNGENAQDQF EYELEQALEA QYKYIVIEPT
RIGDETARWV TVGNCLHKTA VLSGTACLLT PLALPAEYSH YVSLPAGVLS LACSTLYGIS
WQFDPCCKYQ VEYDAYKLSR LPLHTLTSSS PVVLVRKDDI HRKRLHNTIA LAALAYCIKK
LYELYSV