ID   TM125_BOVIN             Reviewed;         219 AA.
AC   Q2HJ59;
DT   03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2006, sequence version 1.
DT   03-AUG-2022, entry version 75.
DE   RecName: Full=Transmembrane protein 125;
GN   Name=TMEM125;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Uterus;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; BC113299; AAI13300.1; -; mRNA.
DR   RefSeq; NP_001039488.1; NM_001046023.2.
DR   RefSeq; XP_005204745.1; XM_005204688.3.
DR   RefSeq; XP_015321524.1; XM_015466038.1.
DR   AlphaFoldDB; Q2HJ59; -.
DR   STRING; 9913.ENSBTAP00000028077; -.
DR   PaxDb; Q2HJ59; -.
DR   PRIDE; Q2HJ59; -.
DR   Ensembl; ENSBTAT00000028077; ENSBTAP00000028077; ENSBTAG00000021082.
DR   GeneID; 509101; -.
DR   KEGG; bta:509101; -.
DR   CTD; 128218; -.
DR   VEuPathDB; HostDB:ENSBTAG00000021082; -.
DR   VGNC; VGNC:35958; TMEM125.
DR   eggNOG; ENOG502S0IK; Eukaryota.
DR   GeneTree; ENSGT00390000003015; -.
DR   HOGENOM; CLU_118850_0_0_1; -.
DR   InParanoid; Q2HJ59; -.
DR   OMA; EHVELWW; -.
DR   OrthoDB; 1443352at2759; -.
DR   TreeFam; TF332758; -.
DR   Proteomes; UP000009136; Chromosome 3.
DR   Bgee; ENSBTAG00000021082; Expressed in pons and 77 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR028165; TMEM125.
DR   PANTHER; PTHR31416; PTHR31416; 1.
DR   Pfam; PF15109; TMEM125; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..219
FT                   /note="Transmembrane protein 125"
FT                   /id="PRO_0000251715"
FT   TRANSMEM        36..56
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        68..88
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        114..134
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        147..167
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   219 AA;  22160 MW;  E21D022D7EED5675 CRC64;
     MSEGEAQAPR GRGLPPDVLA EQVELWWSQQ PRRSALCFAV AVGLVAGCGA GGVALLSSTS
     SRSGEWRLAV GTALCLLALL VLVKQLMSSA VQDMNCIRQP HHVALLRSGG GADALVVLLS
     GLVLLVTGLT LAGLAAAPAP ARPLAAMLSV GITLAASGAL LLLGLLLYQV AVSGHCPPAR
     TAAPTTRSDR SGNGSVFSIS GQLSAGQRHE TTSSIASLI