ID   TM129_CHICK             Reviewed;         362 AA.
AC   Q5ZI25;
DT   12-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 68.
DE   RecName: Full=Transmembrane protein 129;
DE   Flags: Precursor;
GN   Name=TMEM129; ORFNames=RCJMB04_31c10;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB; TISSUE=Bursa of Fabricius;
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TMEM129 family. {ECO:0000305}.
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DR   EMBL; AJ720959; CAG32618.1; -; mRNA.
DR   RefSeq; NP_001026339.1; NM_001031168.1.
DR   AlphaFoldDB; Q5ZI25; -.
DR   STRING; 9031.ENSGALP00000025289; -.
DR   PaxDb; Q5ZI25; -.
DR   GeneID; 422900; -.
DR   KEGG; gga:422900; -.
DR   CTD; 92305; -.
DR   VEuPathDB; HostDB:geneid_422900; -.
DR   eggNOG; KOG3899; Eukaryota.
DR   InParanoid; Q5ZI25; -.
DR   OrthoDB; 647242at2759; -.
DR   PhylomeDB; Q5ZI25; -.
DR   PRO; PR:Q5ZI25; -.
DR   Proteomes; UP000000539; Unplaced.
DR   GO; GO:0005783; C:endoplasmic reticulum; IBA:GO_Central.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0061630; F:ubiquitin protein ligase activity; IBA:GO_Central.
DR   InterPro; IPR018801; TM129.
DR   PANTHER; PTHR31322; PTHR31322; 1.
DR   Pfam; PF10272; Tmpp129; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Signal; Transmembrane; Transmembrane helix.
FT   SIGNAL          1..28
FT                   /evidence="ECO:0000255"
FT   CHAIN           29..362
FT                   /note="Transmembrane protein 129"
FT                   /id="PRO_0000291043"
FT   TOPO_DOM        29..57
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        58..78
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        79..94
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        95..115
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        116..362
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   362 AA;  40962 MW;  B1D2A68B1732C8C7 CRC64;
     MESPAVTFTL AYLVFAVCFV FPPDEVRSAG LTVQSLLAAW LGSEDAAFVQ YHLRRSTGTL
     LAHSLLPLGY YFGMCFAAPE KHLCFFYLAS KEWKTFFFFA VLLPAVSSTM AYYWSRKGWN
     NHPLARTLAV YALPQSGWRA VASSINTEFR RIDKFATGAP GARVIVTDTW VIKVTTYCLH
     VAQQQDIHLT VTDSRQHELT PDSNMPVQFL TIRVASVNPY VKAFDIRLNS AEYGELREKL
     RAPISNAANV VIHQSLSDLF LETFTSLVEM NQTYSVPSTQ ELEPCIGCMQ TIANIKLIKN
     CQEPNEGECQ QCYCRPMWCL TCMGKWFASR QDQQHPETWL SSHVPCPTCR AKFCILDVCI
     IR