ID   TM140_RAT               Reviewed;         184 AA.
AC   Q5M826;
DT   06-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-2005, sequence version 1.
DT   03-AUG-2022, entry version 77.
DE   RecName: Full=Transmembrane protein 140;
GN   Name=Tmem140;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Liver;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC088293; AAH88293.1; -; mRNA.
DR   RefSeq; NP_001009709.1; NM_001009709.1.
DR   AlphaFoldDB; Q5M826; -.
DR   STRING; 10116.ENSRNOP00000031501; -.
DR   GlyGen; Q5M826; 1 site.
DR   PaxDb; Q5M826; -.
DR   Ensembl; ENSRNOT00000029845; ENSRNOP00000031501; ENSRNOG00000026965.
DR   GeneID; 362334; -.
DR   KEGG; rno:362334; -.
DR   UCSC; RGD:1549759; rat.
DR   CTD; 55281; -.
DR   RGD; 1549759; Tmem140.
DR   eggNOG; ENOG502S6FP; Eukaryota.
DR   GeneTree; ENSGT00390000014089; -.
DR   HOGENOM; CLU_125527_0_0_1; -.
DR   InParanoid; Q5M826; -.
DR   OMA; NFCLWNQ; -.
DR   OrthoDB; 1420340at2759; -.
DR   PhylomeDB; Q5M826; -.
DR   TreeFam; TF336296; -.
DR   PRO; PR:Q5M826; -.
DR   Proteomes; UP000002494; Chromosome 4.
DR   Bgee; ENSRNOG00000026965; Expressed in liver and 18 other tissues.
DR   Genevisible; Q5M826; RN.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR028038; TM140.
DR   PANTHER; PTHR16103; PTHR16103; 1.
DR   Pfam; PF14985; TM140; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..184
FT                   /note="Transmembrane protein 140"
FT                   /id="PRO_0000274359"
FT   TOPO_DOM        1..12
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        13..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        34..83
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        84..104
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        105..117
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        118..138
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        139..149
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        150..170
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        171..184
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        37
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   184 AA;  20497 MW;  1548D4A07D7BF83B CRC64;
     MAISRVWRNR LSFMAIMILV AMVLSLMSYA LLWKAGNLTD VPNLRIGFYN FCLWKEDIGS
     LECYNFPELG VLGIPQVGLA LARLGVYGAL VLAVFVPLPL LLAQCNSDEG EWRLAVGFLG
     ASSVLLAGGL SLFLFLVWKW LRLSFLGPGF LSLCLAQALL IILLMAMVMF PPRDKKDKNH
     WENC