TM144_CAEEL
ID TM144_CAEEL Reviewed; 345 AA.
AC Q10000; Q629J4;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 26-APR-2005, sequence version 3.
DT 03-AUG-2022, entry version 110.
DE RecName: Full=Transmembrane protein 144 homolog;
GN ORFNames=R144.6;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the TMEM144 family. {ECO:0000305}.
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DR EMBL; FO080694; CCD65875.1; -; Genomic_DNA.
DR RefSeq; NP_498062.2; NM_065661.4.
DR AlphaFoldDB; Q10000; -.
DR BioGRID; 40911; 1.
DR STRING; 6239.R144.6; -.
DR TCDB; 2.A.7.8.1; the drug/metabolite transporter (dmt) superfamily.
DR EPD; Q10000; -.
DR PaxDb; Q10000; -.
DR PeptideAtlas; Q10000; -.
DR EnsemblMetazoa; R144.6.1; R144.6.1; WBGene00020096.
DR GeneID; 175678; -.
DR KEGG; cel:CELE_R144.6; -.
DR UCSC; R144.6; c. elegans.
DR CTD; 175678; -.
DR WormBase; R144.6; CE37549; WBGene00020096; -.
DR eggNOG; ENOG502QR0F; Eukaryota.
DR GeneTree; ENSGT00390000012574; -.
DR HOGENOM; CLU_031844_1_0_1; -.
DR InParanoid; Q10000; -.
DR OMA; GALWCTG; -.
DR OrthoDB; 960736at2759; -.
DR PhylomeDB; Q10000; -.
DR PRO; PR:Q10000; -.
DR Proteomes; UP000001940; Chromosome III.
DR Bgee; WBGene00020096; Expressed in germ line (C elegans) and 4 other tissues.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0015144; F:carbohydrate transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR010651; Sugar_transport.
DR InterPro; IPR012435; TMEM144.
DR PANTHER; PTHR16119; PTHR16119; 1.
DR Pfam; PF07857; TMEM144; 1.
PE 3: Inferred from homology;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..345
FT /note="Transmembrane protein 144 homolog"
FT /id="PRO_0000065442"
FT TRANSMEM 3..23
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 32..52
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 61..81
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 84..104
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 120..140
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 193..213
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 233..253
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 265..285
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 293..313
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 324..344
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 345 AA; 36897 MW; 58A960F8041077FD CRC64;
MSIAVGLSAC ALSSVLFGSM FVPVKKCHSG NGIFVQWIMS TAILLVGIVV YSTQGFPEFE
PLAMLGGMFW ALGNATAVPI MNTIGIGMGM LVWGTTNCVA GWAAGRFGLF GINSTVPEYP
FLNYFGLVLV VFGGFLFSQI RPNEPQTASE RSPLMVAPDD DLTDDVAPDD SDIVVPRGGA
VPTRAHRNQK RLLAIITSLV AGVFYGFTFV PVIYIQDHPE IYPTAPKTGL GYVFSHYIGI
FCTASALMIG YVIYSRNNPF ASSRLVGPSM TAGSMWGIAQ ASWFVANDNL SQAVSFPIIS
MVPGVIAALW SVFYFRDISG SRNLRLLSIA VAITLIGAIC VGVSK
