ID   TM145_XENLA             Reviewed;         547 AA.
AC   Q5U239;
DT   20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   07-DEC-2004, sequence version 1.
DT   03-AUG-2022, entry version 47.
DE   RecName: Full=Transmembrane protein 145;
GN   Name=tmem145;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Eye;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; BC086291; AAH86291.1; -; mRNA.
DR   RefSeq; NP_001088644.1; NM_001095175.1.
DR   AlphaFoldDB; Q5U239; -.
DR   DNASU; 495696; -.
DR   GeneID; 495696; -.
DR   KEGG; xla:495696; -.
DR   CTD; 495696; -.
DR   Xenbase; XB-GENE-977885; tmem145.L.
DR   OMA; YTWSGCA; -.
DR   OrthoDB; 1155958at2759; -.
DR   Proteomes; UP000186698; Chromosome 7L.
DR   Bgee; 495696; Expressed in brain and 16 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0019236; P:response to pheromone; IEA:InterPro.
DR   InterPro; IPR019336; Intimal_thickness-rel_rcpt.
DR   Pfam; PF10192; GpcrRhopsn4; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..547
FT                   /note="Transmembrane protein 145"
FT                   /id="PRO_0000280357"
FT   TRANSMEM        2..22
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        182..202
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        214..234
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        248..268
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        283..303
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        325..345
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        356..376
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        388..408
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        28
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        102
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        243
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        443
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        453
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        464
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   547 AA;  61754 MW;  351EE629EB4DF3AE CRC64;
     MGPHAGPGML LLLLGFLRIS AAKYVRGNLT TKEDWVFLTR FCFLSDYGRL EFKFKYPEAK
     CCQNILLYFD DTSQWPAVYK KDNKDCLMKE SVIRPENNQV INLTTQYVWS GCQVIKEAGQ
     SYLSCNSGRS FRSVRERWWY IALSKCGGDG LQLEYEMTLT NGKSFWTRHF SADEFGILET
     DITFLLIFIL ILLLSCYFGY ILRGRQLLHT TYKMFMAAAG VEVLSLLLFC VYWGQYAQDG
     VGNSSIKVLA KLLFSASFLI FLLMLILLGK GFTVTRGRIS HLGSIKLSVY MTLYTVTHTV
     LFIHEAQFFD PAQVLYTYES PAGYGNIALQ FLAYIWFCYA VLVTLKHFPE KQAFYVPFFA
     AYTLWFFAVP VMALIANFGI PKWAREKIVN GIQLGIHLYA HAVFLIITRP SAANKNFPYH
     VRTSQIGIME QSTEKFPHHV YGNVTFISDS VPNVTELFSI PSSNGSSAGI TKPVPYPVTL
     GQCYSQLTSD SHQVISPPLL NGVPGVQKVP VGETQLGGLQ QLHAPQIHHQ NGFPEYFSIR
     SAGPQPM