TM160_MOUSE
ID TM160_MOUSE Reviewed; 188 AA.
AC Q9D938; Q3TKH9;
DT 20-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 110.
DE RecName: Full=Transmembrane protein 160;
GN Name=Tmem160;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Blastocyst, and Pancreas;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Mammary gland;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the TMEM160 family. {ECO:0000305}.
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DR EMBL; AK007386; BAB25003.1; -; mRNA.
DR EMBL; AK166985; BAE39166.1; -; mRNA.
DR EMBL; BC028534; AAH28534.1; -; mRNA.
DR CCDS; CCDS20849.1; -.
DR RefSeq; NP_081214.1; NM_026938.1.
DR AlphaFoldDB; Q9D938; -.
DR BioGRID; 213224; 6.
DR STRING; 10090.ENSMUSP00000019302; -.
DR iPTMnet; Q9D938; -.
DR PhosphoSitePlus; Q9D938; -.
DR EPD; Q9D938; -.
DR MaxQB; Q9D938; -.
DR PaxDb; Q9D938; -.
DR PeptideAtlas; Q9D938; -.
DR PRIDE; Q9D938; -.
DR ProteomicsDB; 259539; -.
DR Antibodypedia; 65063; 14 antibodies from 12 providers.
DR DNASU; 69094; -.
DR Ensembl; ENSMUST00000019302; ENSMUSP00000019302; ENSMUSG00000019158.
DR GeneID; 69094; -.
DR KEGG; mmu:69094; -.
DR UCSC; uc009fhu.1; mouse.
DR CTD; 54958; -.
DR MGI; MGI:1916344; Tmem160.
DR VEuPathDB; HostDB:ENSMUSG00000019158; -.
DR eggNOG; ENOG502S3E7; Eukaryota.
DR GeneTree; ENSGT00390000012863; -.
DR HOGENOM; CLU_110295_0_0_1; -.
DR InParanoid; Q9D938; -.
DR OMA; GCNLPEA; -.
DR OrthoDB; 1344928at2759; -.
DR PhylomeDB; Q9D938; -.
DR TreeFam; TF338764; -.
DR BioGRID-ORCS; 69094; 3 hits in 72 CRISPR screens.
DR ChiTaRS; Tmem160; mouse.
DR PRO; PR:Q9D938; -.
DR Proteomes; UP000000589; Chromosome 7.
DR RNAct; Q9D938; protein.
DR Bgee; ENSMUSG00000019158; Expressed in choroid plexus of fourth ventricle and 250 other tissues.
DR ExpressionAtlas; Q9D938; baseline and differential.
DR Genevisible; Q9D938; MM.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005739; C:mitochondrion; HDA:MGI.
DR InterPro; IPR026801; TMEM160.
DR PANTHER; PTHR16236; PTHR16236; 1.
PE 2: Evidence at transcript level;
KW Membrane; Phosphoprotein; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..188
FT /note="Transmembrane protein 160"
FT /id="PRO_0000277811"
FT TRANSMEM 70..90
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 102..122
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 135..155
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 21..53
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 168..188
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 48
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q9NX00"
SQ SEQUENCE 188 AA; 19587 MW; 834F25801CF27607 CRC64;
MGGGWWWARV ARLARLRFRG SLQPPQRPRS GGARGSFAPG HGPRAGASPP PVSELDRADA
WLLRKAHETA FLSWFRNGLL SSGIGVISFM QSDMGREAAY GFFLLGGLCV VWGGASYAVG
LAALRGPMQL SLAGAAAGVG AVLAASLLWA CAVGLYMGQL ELDVELVPED DGAASTEGPD
EAGRPPPE
