ID   TM170_DICDI             Reviewed;         128 AA.
AC   Q54GN6;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   03-AUG-2022, entry version 60.
DE   RecName: Full=Transmembrane protein 170 homolog;
GN   Name=tmem170; ORFNames=DDB_G0290053;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TMEM170 family. {ECO:0000305}.
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DR   EMBL; AAFI02000151; EAL62432.1; -; Genomic_DNA.
DR   RefSeq; XP_635926.1; XM_630834.1.
DR   AlphaFoldDB; Q54GN6; -.
DR   SMR; Q54GN6; -.
DR   PaxDb; Q54GN6; -.
DR   EnsemblProtists; EAL62432; EAL62432; DDB_G0290053.
DR   GeneID; 8627447; -.
DR   KEGG; ddi:DDB_G0290053; -.
DR   dictyBase; DDB_G0290053; tmem170.
DR   eggNOG; ENOG502SYB0; Eukaryota.
DR   HOGENOM; CLU_161007_0_0_1; -.
DR   InParanoid; Q54GN6; -.
DR   OMA; ITFWCTV; -.
DR   PhylomeDB; Q54GN6; -.
DR   PRO; PR:Q54GN6; -.
DR   Proteomes; UP000002195; Chromosome 5.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR019334; Transmembrane_pr_170.
DR   PANTHER; PTHR22779; PTHR22779; 1.
DR   Pfam; PF10190; Tmemb_170; 1.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..128
FT                   /note="Transmembrane protein 170 homolog"
FT                   /id="PRO_0000328235"
FT   TRANSMEM        32..52
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        74..94
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        98..118
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   128 AA;  14229 MW;  164304E43A8819C5 CRC64;
     MPFRDSLQPD TRYLTDGSLF HGYFYQYGDI WLAITFWCTV VTTISYLISG FVASFVLKKS
     KFSPFIPIFT AMYGMAIGIC YGGISALILS AIYVSGSFLL SWYQGIICGV GLAIVHLLFA
     FTQGKLQV