ID   TM171_BOVIN             Reviewed;         326 AA.
AC   Q58DS4; Q3SZB9;
DT   19-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT   26-APR-2005, sequence version 1.
DT   03-AUG-2022, entry version 67.
DE   RecName: Full=Transmembrane protein 171;
GN   Name=TMEM171;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX   PubMed=16305752; DOI=10.1186/1471-2164-6-166;
RA   Harhay G.P., Sonstegard T.S., Keele J.W., Heaton M.P., Clawson M.L.,
RA   Snelling W.M., Wiedmann R.T., Van Tassell C.P., Smith T.P.L.;
RT   "Characterization of 954 bovine full-CDS cDNA sequences.";
RL   BMC Genomics 6:166-166(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Ileum;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; BT021523; AAX46370.1; -; mRNA.
DR   EMBL; BC102968; AAI02969.1; -; mRNA.
DR   RefSeq; NP_001014951.2; NM_001014951.3.
DR   RefSeq; XP_005221470.1; XM_005221413.2.
DR   AlphaFoldDB; Q58DS4; -.
DR   STRING; 9913.ENSBTAP00000036676; -.
DR   PaxDb; Q58DS4; -.
DR   Ensembl; ENSBTAT00000011197; ENSBTAP00000011197; ENSBTAG00000008494.
DR   Ensembl; ENSBTAT00000036824; ENSBTAP00000036676; ENSBTAG00000008494.
DR   GeneID; 538802; -.
DR   KEGG; bta:538802; -.
DR   CTD; 134285; -.
DR   VEuPathDB; HostDB:ENSBTAG00000008494; -.
DR   VGNC; VGNC:35996; TMEM171.
DR   eggNOG; ENOG502QRR0; Eukaryota.
DR   GeneTree; ENSGT00390000017024; -.
DR   HOGENOM; CLU_900031_0_0_1; -.
DR   InParanoid; Q58DS4; -.
DR   OMA; QNEQVYS; -.
DR   OrthoDB; 1046807at2759; -.
DR   TreeFam; TF335590; -.
DR   Proteomes; UP000009136; Chromosome 20.
DR   Bgee; ENSBTAG00000008494; Expressed in rumen papilla and 68 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR029173; TMEM171.
DR   PANTHER; PTHR31617; PTHR31617; 1.
DR   Pfam; PF15471; TMEM171; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..326
FT                   /note="Transmembrane protein 171"
FT                   /id="PRO_0000249573"
FT   TRANSMEM        22..42
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        57..77
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        114..134
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        161..181
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          229..326
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        254..268
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        282..297
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        325
FT                   /note="P -> L (in Ref. 2; AAI02969)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   326 AA;  34911 MW;  7A48DE432B9FD47F CRC64;
     MSPAAAAEPD GVRGDRHVSK LIFFLFVIGA ILLCVGVLLS IFGFQACQYK TFPDCSMMLK
     IAGPACAVVG LGAVILARSR ARLQQTEERL RGNNQADSDR PFLCGESRQF VQCLIFGFLF
     LTSGMLISVL GIWVPGCGSD WMQESLNETD TADSEPQICG FLSLQILGPL IVLVGLCFFV
     VAHVKKRSNL NGDQDASESE ERQTQSLEPI QVTVGDAVII FPPPPPPYFP ESSASAAARS
     PGTDGLLPDE SPPSYYSIFQ SGSPTPEGQG AASERDCELI YTISGTASSS ETSHTLHLLS
     ELPPRYEEKE TATTTSLSPS SEPSPP