TM171_MOUSE
ID TM171_MOUSE Reviewed; 322 AA.
AC Q4KL18;
DT 19-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT 02-AUG-2005, sequence version 1.
DT 03-AUG-2022, entry version 86.
DE RecName: Full=Transmembrane protein 171;
GN Name=Tmem171; Synonyms=Gm905;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Placenta;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
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DR EMBL; BC099490; AAH99490.1; -; mRNA.
DR CCDS; CCDS26716.1; -.
DR RefSeq; NP_001020777.1; NM_001025606.1.
DR AlphaFoldDB; Q4KL18; -.
DR STRING; 10090.ENSMUSP00000070369; -.
DR PhosphoSitePlus; Q4KL18; -.
DR MaxQB; Q4KL18; -.
DR PaxDb; Q4KL18; -.
DR PRIDE; Q4KL18; -.
DR ProteomicsDB; 260683; -.
DR Antibodypedia; 24256; 18 antibodies from 11 providers.
DR Ensembl; ENSMUST00000064347; ENSMUSP00000070369; ENSMUSG00000052485.
DR GeneID; 380863; -.
DR KEGG; mmu:380863; -.
DR UCSC; uc007roy.1; mouse.
DR CTD; 134285; -.
DR MGI; MGI:2685751; Tmem171.
DR VEuPathDB; HostDB:ENSMUSG00000052485; -.
DR eggNOG; ENOG502QRR0; Eukaryota.
DR GeneTree; ENSGT00390000017024; -.
DR HOGENOM; CLU_900031_0_0_1; -.
DR InParanoid; Q4KL18; -.
DR OMA; QNEQVYS; -.
DR OrthoDB; 1046807at2759; -.
DR PhylomeDB; Q4KL18; -.
DR TreeFam; TF335590; -.
DR BioGRID-ORCS; 380863; 0 hits in 74 CRISPR screens.
DR PRO; PR:Q4KL18; -.
DR Proteomes; UP000000589; Chromosome 13.
DR RNAct; Q4KL18; protein.
DR Bgee; ENSMUSG00000052485; Expressed in interventricular septum and 49 other tissues.
DR ExpressionAtlas; Q4KL18; baseline and differential.
DR Genevisible; Q4KL18; MM.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR029173; TMEM171.
DR PANTHER; PTHR31617; PTHR31617; 1.
DR Pfam; PF15471; TMEM171; 1.
PE 2: Evidence at transcript level;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..322
FT /note="Transmembrane protein 171"
FT /id="PRO_0000249571"
FT TRANSMEM 22..42
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 57..77
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 112..132
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 159..179
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 223..322
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 234..268
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 275..291
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 322 AA; 34585 MW; 9D29C951B768AF1D CRC64;
MSSVGTAEPD GDQRDRHVSK LIFFLFVFGA ALLCVGVLLS IFGYQACQYK PLSHCSIVLK
IAGPSCAVVG LGAVILARSR ARLHLRERQR QGLQDPDQSF FCGESRQFAQ CLIFGFLFLT
SGMLISILGI WVPGCDSDWA QEPLNETNTG EGEPQICGFL SLQIMGPLVV LVGLCFFVVA
HVKKKNNLSS SRDTSEVEGG HAHSTEPVHI TVGDSVIIFP PPPPPYFPES SAAAPSPGAN
SLHQIENPPS YSSLFNYGTP TPENQGAASE REQELIYTIS GQGSSSERSY TGHLPLDLPP
RYEEKETAPA TPLGAPSDAS PP
