ID   TM174_PONAB             Reviewed;         243 AA.
AC   Q5R8E0;
DT   03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   25-MAY-2022, entry version 56.
DE   RecName: Full=Transmembrane protein 174;
GN   Name=TMEM174;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250};
CC       Multi-pass membrane protein {ECO:0000250}.
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DR   EMBL; CR859813; CAH91970.1; -; mRNA.
DR   RefSeq; NP_001126141.1; NM_001132669.2.
DR   AlphaFoldDB; Q5R8E0; -.
DR   STRING; 9601.ENSPPYP00000017379; -.
DR   Ensembl; ENSPPYT00000018084; ENSPPYP00000017379; ENSPPYG00000015548.
DR   GeneID; 100173099; -.
DR   KEGG; pon:100173099; -.
DR   CTD; 134288; -.
DR   eggNOG; ENOG502RZ98; Eukaryota.
DR   GeneTree; ENSGT00390000004161; -.
DR   HOGENOM; CLU_099888_0_0_1; -.
DR   InParanoid; Q5R8E0; -.
DR   OMA; YYTIYPP; -.
DR   OrthoDB; 1122990at2759; -.
DR   TreeFam; TF335512; -.
DR   Proteomes; UP000001595; Chromosome 5.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR027835; TMEM174.
DR   PANTHER; PTHR31020; PTHR31020; 1.
DR   Pfam; PF15029; TMEM174; 1.
PE   2: Evidence at transcript level;
KW   Endoplasmic reticulum; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..243
FT                   /note="Transmembrane protein 174"
FT                   /id="PRO_0000282579"
FT   TRANSMEM        40..60
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        73..93
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   243 AA;  26217 MW;  9390E330E5B86E5F CRC64;
     MEQGSGRLED FPVNVFSVTP YTPSTADIQV SDDDKAGATL LFSGIFLGLV GITFTVMGWI
     KYQGVSHFEW TQLLGPVLLS VGVTFILIAV CKFKMLSCQL CKESEERVLD SEQTPGGPSF
     VFTGINQPIT FHGATVVQYI PPPYGSPEPV GINTSYLQSV VSPCSLITSG GAAAAMSSPS
     QYYTIYPQDN SAFVVDEGCP SFADGGNHRP NPDADQLEET QLEEEACACF SPPPYEEIYS
     LPR