ID   TM183_PONAB             Reviewed;         387 AA.
AC   Q5R8D5;
DT   16-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2005, sequence version 2.
DT   25-MAY-2022, entry version 46.
DE   RecName: Full=Transmembrane protein 183;
GN   Name=TMEM183;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TMEM183 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAH91975.1; Type=Erroneous termination; Note=Truncated C-terminus.; Evidence={ECO:0000305};
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DR   EMBL; CR859818; CAH91975.1; ALT_TERM; mRNA.
DR   AlphaFoldDB; Q5R8D5; -.
DR   STRING; 9601.ENSPPYP00000000376; -.
DR   eggNOG; ENOG502QS4U; Eukaryota.
DR   InParanoid; Q5R8D5; -.
DR   Proteomes; UP000001595; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR036047; F-box-like_dom_sf.
DR   InterPro; IPR026509; TMEM183.
DR   PANTHER; PTHR20988; PTHR20988; 1.
DR   SUPFAM; SSF81383; SSF81383; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..387
FT                   /note="Transmembrane protein 183"
FT                   /id="PRO_0000089253"
FT   TRANSMEM        299..319
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          99..126
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   387 AA;  44168 MW;  85F3B69B402A2AC3 CRC64;
     MARGPGPLGR PRPDTVAMPK RGKRLKFRAH DACSGRVTVA DYANSDPAVV RSGRVKKAVA
     NAVQQEVKSL CGLEASQVPT EEALSGAGEP CDIIDSSDEM EAQEESIHER TVSRKKKSKR
     HKEELDGAGE EYPMDIWLLL ASYIRPEDIV NFSLICKNAW TVTCTAAFWT RLYRRHYTLD
     ASLPLRLRPE SMEKLRCLRA CVIRSLYHMY EPFAARISKN PAIPESTPST LKNSKCLLFW
     CRKIVGNRQE PMWEFNFKFK KQSPRLKSKC TGGLQPPVQY EDVHTNPDQD CCLLQVTTLN
     FIFIPIVMGM IFTLFTINVS TDMRHHRVRL VFQDSPVHGG RKPRSEQGVQ VILDPVHSVR
     LFDWWHPQYP FSLRALLLPI PWGQPRV