TM184_SCHPO
ID TM184_SCHPO Reviewed; 426 AA.
AC Q09906;
DT 01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1996, sequence version 1.
DT 25-MAY-2022, entry version 123.
DE RecName: Full=Transmembrane protein 184 homolog C30D11.06c;
GN ORFNames=SPAC30D11.06c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-364, AND IDENTIFICATION BY
RP MASS SPECTROMETRY.
RX PubMed=18257517; DOI=10.1021/pr7006335;
RA Wilson-Grady J.T., Villen J., Gygi S.P.;
RT "Phosphoproteome analysis of fission yeast.";
RL J. Proteome Res. 7:1088-1097(2008).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the TMEM184 family. {ECO:0000305}.
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DR EMBL; CU329670; CAA91892.1; -; Genomic_DNA.
DR PIR; T38593; S62564.
DR RefSeq; NP_593211.1; NM_001018607.2.
DR PDB; 6AAF; X-ray; 2.20 A; B=386-409.
DR PDBsum; 6AAF; -.
DR AlphaFoldDB; Q09906; -.
DR SMR; Q09906; -.
DR BioGRID; 279501; 2.
DR STRING; 4896.SPAC30D11.06c.1; -.
DR TCDB; 2.A.82.1.8; the organic solute transporter (ost) family.
DR iPTMnet; Q09906; -.
DR PaxDb; Q09906; -.
DR EnsemblFungi; SPAC30D11.06c.1; SPAC30D11.06c.1:pep; SPAC30D11.06c.
DR GeneID; 2543068; -.
DR KEGG; spo:SPAC30D11.06c; -.
DR PomBase; SPAC30D11.06c; -.
DR VEuPathDB; FungiDB:SPAC30D11.06c; -.
DR eggNOG; KOG2641; Eukaryota.
DR HOGENOM; CLU_012923_4_0_1; -.
DR InParanoid; Q09906; -.
DR OMA; AFAIAHW; -.
DR PhylomeDB; Q09906; -.
DR PRO; PR:Q09906; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0071627; C:integral component of fungal-type vacuolar membrane; EXP:PomBase.
DR GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR GO; GO:0022857; F:transmembrane transporter activity; ISM:PomBase.
DR GO; GO:0055085; P:transmembrane transport; ISM:PomBase.
DR GO; GO:0007033; P:vacuole organization; IMP:PomBase.
DR InterPro; IPR005178; Ostalpha/TMEM184C.
DR PANTHER; PTHR23423; PTHR23423; 1.
DR Pfam; PF03619; Solute_trans_a; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Membrane; Phosphoprotein; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..426
FT /note="Transmembrane protein 184 homolog C30D11.06c"
FT /id="PRO_0000211557"
FT TRANSMEM 39..59
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 73..93
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 133..153
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 172..192
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 223..243
FT /note="Helical"
FT /evidence="ECO:0000255"
FT MOD_RES 364
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18257517"
FT TURN 392..394
FT /evidence="ECO:0007829|PDB:6AAF"
FT HELIX 395..403
FT /evidence="ECO:0007829|PDB:6AAF"
SQ SEQUENCE 426 AA; 49290 MW; 9634A50D799C3078 CRC64;
MDNEIVALCG FFVAIALVLS CISIITHLKN YKKPVLQRSV VRILMMIVIY SSVSFLSVYN
EKIGSIFEPF REIYEAFALY CFFCLLIDYL GGERAAVISL HGHLPRPRLW PLNYLQDDID
LSDPYTFLSI KRGILQYTWL KPFLVIAVLL TKVTGVYDRE DQPVYASADL WIGLVYNISI
TLSLYSLTTF WVCLHEELAP FRPFPKFLSV KAIIFASYWQ QTVLSITNWL GLLNGTGWIY
SLLNQNVLMC LEMPFFALSH WYAFRIEDYD TPTWLSCARL PLLKAFKDVI GLKDVWCDSL
QTLHGDRYVY QNFEPGENLI PSRNDGRINR TSHGLRYSQG GQSKYWISRY DQSRVRLINN
SQNSPQSNKS YFSIPGMSTS HFENGLQFEI DDEMEPLYNQ AKQMRYGDYN YPVLLVNNTH
ASSSYT
