ID   TM187_BOVIN             Reviewed;         256 AA.
AC   Q0VCM2;
DT   03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   03-AUG-2022, entry version 72.
DE   RecName: Full=Transmembrane protein 187;
GN   Name=TMEM187;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Fetal liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; BC120100; AAI20101.1; -; mRNA.
DR   RefSeq; NP_001068823.1; NM_001075355.2.
DR   RefSeq; XP_005227742.1; XM_005227685.3.
DR   RefSeq; XP_005227744.1; XM_005227687.3.
DR   RefSeq; XP_005227745.1; XM_005227688.3.
DR   RefSeq; XP_010819862.1; XM_010821560.2.
DR   RefSeq; XP_010819863.1; XM_010821561.2.
DR   RefSeq; XP_015316999.1; XM_015461513.1.
DR   AlphaFoldDB; Q0VCM2; -.
DR   STRING; 9913.ENSBTAP00000010891; -.
DR   PaxDb; Q0VCM2; -.
DR   Ensembl; ENSBTAT00000010891; ENSBTAP00000010891; ENSBTAG00000008278.
DR   GeneID; 508380; -.
DR   KEGG; bta:508380; -.
DR   CTD; 8269; -.
DR   VEuPathDB; HostDB:ENSBTAG00000008278; -.
DR   VGNC; VGNC:36014; TMEM187.
DR   eggNOG; ENOG502QUS7; Eukaryota.
DR   GeneTree; ENSGT00390000011272; -.
DR   HOGENOM; CLU_093204_0_0_1; -.
DR   InParanoid; Q0VCM2; -.
DR   OMA; FLAMPCN; -.
DR   OrthoDB; 1348522at2759; -.
DR   TreeFam; TF353833; -.
DR   Proteomes; UP000009136; Chromosome X.
DR   Bgee; ENSBTAG00000008278; Expressed in liver and 100 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0030133; C:transport vesicle; IBA:GO_Central.
DR   InterPro; IPR028066; TMEM187.
DR   PANTHER; PTHR15066; PTHR15066; 1.
DR   Pfam; PF15100; TMEM187; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..256
FT                   /note="Transmembrane protein 187"
FT                   /id="PRO_0000282915"
FT   TRANSMEM        8..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        51..71
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        94..112
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        119..139
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        146..168
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        193..213
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        233..253
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   256 AA;  28479 MW;  A5E23417E5AF4C93 CRC64;
     MKPESGQALF HVALASCLCV ATVHTGIFEH VSVQVGYEYY AEAPVTSLPA FLAMPFNSLV
     NMAYVFLGVY WLRSQARAPG GPAERRRARY LKDVFAGMAL VYGPVQWLRI GMQTQPTAVL
     DQWLTLPIFA WPVAWCLCLD RGWKPWLFLA VEGLSLCSYS LALLHPHGFE LALGLHIAAA
     VGQALRIQGR HGNISSGTYL ALGVLSCLGF VVLKLCDHEL AQWHLFQQLT GHFWSKVCDV
     LQFHFAFLFL TSLHTC