ID   TM196_XENTR             Reviewed;         177 AA.
AC   A4IIU3;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2007, sequence version 1.
DT   03-AUG-2022, entry version 61.
DE   RecName: Full=Transmembrane protein 196;
GN   Name=tmem196;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; BC136156; AAI36157.1; -; mRNA.
DR   RefSeq; NP_001096449.1; NM_001102979.1.
DR   AlphaFoldDB; A4IIU3; -.
DR   STRING; 8364.ENSXETP00000046264; -.
DR   PaxDb; A4IIU3; -.
DR   DNASU; 100125062; -.
DR   GeneID; 100125062; -.
DR   KEGG; xtr:100125062; -.
DR   CTD; 256130; -.
DR   Xenbase; XB-GENE-950737; tmem196.
DR   eggNOG; ENOG502RXKV; Eukaryota.
DR   HOGENOM; CLU_129608_0_0_1; -.
DR   InParanoid; A4IIU3; -.
DR   OMA; CAWKRTG; -.
DR   OrthoDB; 1518382at2759; -.
DR   PhylomeDB; A4IIU3; -.
DR   TreeFam; TF332520; -.
DR   Proteomes; UP000008143; Chromosome 6.
DR   Proteomes; UP000790000; Unplaced.
DR   ExpressionAtlas; A4IIU3; baseline.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR037661; TMEM196.
DR   PANTHER; PTHR28681; PTHR28681; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..177
FT                   /note="Transmembrane protein 196"
FT                   /id="PRO_0000317259"
FT   TRANSMEM        11..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        47..67
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        73..93
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        106..126
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          152..177
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   177 AA;  19158 MW;  BD8ED440B4577D1E CRC64;
     MCTSRQIIGS LLVLSVLEIG LGLSSVAVGA VTFFRVRMEQ KPQLGDSSPV WSGACFLICG
     VCGIFCAKKK SGLIMILFSA CCICGLIGGI LNIQFLRALN KRSSSLYSLY LASMSLACIG
     ISGCTISTWL TCRLASYEQR RMFLEREHSL HHSHEMTEKD TENITNGGGP LALNGRV