ID   TM205_DANRE             Reviewed;         188 AA.
AC   A1L2F6;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   06-FEB-2007, sequence version 1.
DT   03-AUG-2022, entry version 75.
DE   RecName: Full=Transmembrane protein 205;
GN   Name=tmem205; ORFNames=zgc:158860;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Olfactory epithelium;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TMEM205 family. {ECO:0000305}.
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DR   EMBL; BC129498; AAI29499.1; -; mRNA.
DR   RefSeq; NP_001074155.1; NM_001080686.1.
DR   RefSeq; XP_005168535.1; XM_005168478.2.
DR   AlphaFoldDB; A1L2F6; -.
DR   STRING; 7955.ENSDARP00000064027; -.
DR   PaxDb; A1L2F6; -.
DR   PeptideAtlas; A1L2F6; -.
DR   Ensembl; ENSDART00000162853; ENSDARP00000137350; ENSDARG00000100677.
DR   Ensembl; ENSDART00000162932; ENSDARP00000136289; ENSDARG00000100677.
DR   Ensembl; ENSDART00000168229; ENSDARP00000135732; ENSDARG00000100677.
DR   GeneID; 791204; -.
DR   KEGG; dre:791204; -.
DR   CTD; 374882; -.
DR   ZFIN; ZDB-GENE-070112-1692; tmem205.
DR   eggNOG; KOG2886; Eukaryota.
DR   GeneTree; ENSGT00390000016298; -.
DR   HOGENOM; CLU_094297_1_1_1; -.
DR   InParanoid; A1L2F6; -.
DR   OMA; FQMRAVE; -.
DR   OrthoDB; 1173611at2759; -.
DR   PhylomeDB; A1L2F6; -.
DR   TreeFam; TF323838; -.
DR   PRO; PR:A1L2F6; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 3.
DR   Bgee; ENSDARG00000100677; Expressed in granulocyte and 22 other tissues.
DR   ExpressionAtlas; A1L2F6; baseline.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR025423; DUF4149.
DR   InterPro; IPR042623; TMEM205.
DR   PANTHER; PTHR46916; PTHR46916; 1.
DR   Pfam; PF13664; DUF4149; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..188
FT                   /note="Transmembrane protein 205"
FT                   /id="PRO_0000317504"
FT   TRANSMEM        18..38
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        54..74
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        86..106
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        168..188
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   188 AA;  21301 MW;  B07590E8AD6D35C4 CRC64;
     MATEGDPTDF VKVLHLLVIS FTWGMQVWVS FIAGFVLISQ VSMHTFGLVQ SKLFPVYFYC
     LLGGNAVSLA VYAVYHPREL LDWHEGIQMS LFFVAVIMAG LNAQWFGPSA TENMLVMQEI
     EKEHGLGNQV GMSSNREGYT KLREQDPKYK EHRSTFYRYH GLSNLCNLIG FFCITVNLIY
     LALNLGTI