ID   TM205_PONAB             Reviewed;         189 AA.
AC   Q5REM8;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   03-AUG-2022, entry version 48.
DE   RecName: Full=Transmembrane protein 205;
GN   Name=TMEM205;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Heart;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TMEM205 family. {ECO:0000305}.
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DR   EMBL; CR857495; CAH89779.1; -; mRNA.
DR   RefSeq; NP_001124814.1; NM_001131342.1.
DR   AlphaFoldDB; Q5REM8; -.
DR   STRING; 9601.ENSPPYP00000010740; -.
DR   Ensembl; ENSPPYT00000011160; ENSPPYP00000010740; ENSPPYG00000009576.
DR   GeneID; 100171672; -.
DR   KEGG; pon:100171672; -.
DR   CTD; 374882; -.
DR   eggNOG; KOG2886; Eukaryota.
DR   GeneTree; ENSGT00390000016298; -.
DR   HOGENOM; CLU_094297_1_1_1; -.
DR   InParanoid; Q5REM8; -.
DR   OrthoDB; 1173611at2759; -.
DR   Proteomes; UP000001595; Chromosome 19.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR025423; DUF4149.
DR   InterPro; IPR042623; TMEM205.
DR   PANTHER; PTHR46916; PTHR46916; 1.
DR   Pfam; PF13664; DUF4149; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..189
FT                   /note="Transmembrane protein 205"
FT                   /id="PRO_0000317503"
FT   TRANSMEM        18..38
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        53..73
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        81..101
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        166..186
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   189 AA;  21184 MW;  EE51C91C441601B5 CRC64;
     MEEGGNLGGL IKMVHLLVLS GAWGMQMWVT FVSGFLLFRS LPRHTFGLVQ SKLFPFYFHI
     SMGCAFVNLC ILASQHAWAQ LTFWEASQLY LLFLSLTLAT VNARWLEPRT TAAMWALQTV
     EKERGLGGEV PGSHQGPDPY RQLREKDPKY SALRQNFFRY HGLSSLCNLG CVLSNGLCLA
     GLALEIRSL