ID   TM205_XENLA             Reviewed;         188 AA.
AC   Q6GPW4;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 48.
DE   RecName: Full=Transmembrane protein 205;
GN   Name=tmem205;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Spleen;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TMEM205 family. {ECO:0000305}.
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DR   EMBL; BC072992; AAH72992.1; -; mRNA.
DR   RefSeq; NP_001085593.1; NM_001092124.1.
DR   RefSeq; XP_018106419.1; XM_018250930.1.
DR   AlphaFoldDB; Q6GPW4; -.
DR   DNASU; 444019; -.
DR   GeneID; 444019; -.
DR   KEGG; xla:444019; -.
DR   CTD; 444019; -.
DR   Xenbase; XB-GENE-5820554; tmem205.L.
DR   OMA; FQMRAVE; -.
DR   Proteomes; UP000186698; Chromosome 3L.
DR   Bgee; 444019; Expressed in internal ear and 20 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR025423; DUF4149.
DR   InterPro; IPR042623; TMEM205.
DR   PANTHER; PTHR46916; PTHR46916; 1.
DR   Pfam; PF13664; DUF4149; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..188
FT                   /note="Transmembrane protein 205"
FT                   /id="PRO_0000317505"
FT   TRANSMEM        18..38
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        53..73
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        89..109
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        168..188
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   188 AA;  21176 MW;  04151AB3889F676C CRC64;
     MVAEGDPGNL VKIFHLLVLS ASWGMQCWMT FVAGFVLIKG VPRHTFGLVQ SKLFPYYNHI
     VLCCSFISLA IYAAYHPREL LSPSESVQIS LFFTSLLVAA LQARWFSPVT TKTMFKMHVI
     EREHSLGQGV GLSANKEGYQ LLQEKDPKYK ALRKRFMRYH GISSLCNLLC LLCNGANLVY
     IALLMPTL