ID   TM207_MOUSE             Reviewed;         143 AA.
AC   P86045;
DT   25-NOV-2008, integrated into UniProtKB/Swiss-Prot.
DT   25-NOV-2008, sequence version 1.
DT   03-AUG-2022, entry version 63.
DE   RecName: Full=Transmembrane protein 207 {ECO:0000312|MGI:MGI:2685386};
DE   Flags: Precursor;
GN   Name=Tmem207 {ECO:0000312|MGI:MGI:2685386};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1] {ECO:0000305}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX   PubMed=16141072; DOI=10.1126/science.1112014;
RA   Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA   Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA   Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA   Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA   Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA   Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA   Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA   Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA   Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA   Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA   Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA   Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA   Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA   Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA   Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA   Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA   Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA   Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA   Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA   Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA   Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA   Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA   Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA   Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA   Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA   van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA   Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA   Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA   Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA   Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA   Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA   Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA   Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA   Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT   "The transcriptional landscape of the mammalian genome.";
RL   Science 309:1559-1563(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J;
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
CC   -!- SUBUNIT: Interacts with WWOX. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Single-pass type I
CC       membrane protein {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AK142524; Type=Miscellaneous discrepancy; Note=Intron retention.; Evidence={ECO:0000305};
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DR   EMBL; AK142524; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; AC154601; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   CCDS; CCDS49813.1; -.
DR   RefSeq; NP_001095110.1; NM_001101640.1.
DR   AlphaFoldDB; P86045; -.
DR   SMR; P86045; -.
DR   STRING; 10090.ENSMUSP00000127563; -.
DR   PhosphoSitePlus; P86045; -.
DR   PaxDb; P86045; -.
DR   PRIDE; P86045; -.
DR   Antibodypedia; 3068; 38 antibodies from 11 providers.
DR   Ensembl; ENSMUST00000165687; ENSMUSP00000127563; ENSMUSG00000091972.
DR   GeneID; 100043057; -.
DR   KEGG; mmu:100043057; -.
DR   UCSC; uc012adv.1; mouse.
DR   CTD; 131920; -.
DR   MGI; MGI:2685386; Tmem207.
DR   VEuPathDB; HostDB:ENSMUSG00000091972; -.
DR   eggNOG; ENOG502STQD; Eukaryota.
DR   GeneTree; ENSGT00390000006126; -.
DR   HOGENOM; CLU_149421_0_0_1; -.
DR   InParanoid; P86045; -.
DR   OMA; SPTVGIH; -.
DR   OrthoDB; 1447750at2759; -.
DR   PhylomeDB; P86045; -.
DR   TreeFam; TF342774; -.
DR   BioGRID-ORCS; 100043057; 3 hits in 74 CRISPR screens.
DR   PRO; PR:P86045; -.
DR   Proteomes; UP000000589; Chromosome 16.
DR   RNAct; P86045; protein.
DR   Bgee; ENSMUSG00000091972; Expressed in right kidney and 7 other tissues.
DR   Genevisible; P86045; MM.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR039490; TMEM207.
DR   PANTHER; PTHR36467; PTHR36467; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Signal; Transmembrane; Transmembrane helix.
FT   SIGNAL          1..29
FT                   /evidence="ECO:0000255"
FT   CHAIN           30..143
FT                   /note="Transmembrane protein 207"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000355136"
FT   TRANSMEM        52..72
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   143 AA;  15808 MW;  ECF866BBD327FF5B CRC64;
     MSTSSPFRVA SKIVTAGCLC LPLFQRVLSD LSCEENEMCV NYDERYPDGW YIWFFLLIFL
     VVLLCGVVLF CLQCWLKRCG INPPRRTMAV FAVGDLDPVY GAEMAGSPTS GICHPTQNTE
     LCSAPCFGAL GPPPPYEEIL KAN