ID   TM209_RAT               Reviewed;         561 AA.
AC   Q68FR5;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=Transmembrane protein 209;
GN   Name=Tmem209;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; BC079399; AAH79399.1; -; mRNA.
DR   RefSeq; NP_001014077.1; NM_001014055.1.
DR   AlphaFoldDB; Q68FR5; -.
DR   STRING; 10116.ENSRNOP00000031535; -.
DR   GlyGen; Q68FR5; 2 sites.
DR   PaxDb; Q68FR5; -.
DR   GeneID; 312200; -.
DR   KEGG; rno:312200; -.
DR   UCSC; RGD:1309682; rat.
DR   CTD; 84928; -.
DR   RGD; 1309682; Tmem209.
DR   VEuPathDB; HostDB:ENSRNOG00000028219; -.
DR   eggNOG; KOG4670; Eukaryota.
DR   InParanoid; Q68FR5; -.
DR   OMA; WDSSLPT; -.
DR   OrthoDB; 1481817at2759; -.
DR   PhylomeDB; Q68FR5; -.
DR   TreeFam; TF320043; -.
DR   PRO; PR:Q68FR5; -.
DR   Proteomes; UP000002494; Chromosome 4.
DR   Bgee; ENSRNOG00000028219; Expressed in testis and 19 other tissues.
DR   ExpressionAtlas; Q68FR5; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IBA:GO_Central.
DR   InterPro; IPR019176; Cytochrome_B561-rel.
DR   PANTHER; PTHR21780; PTHR21780; 1.
DR   Pfam; PF09786; CytochromB561_N; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Membrane; Phosphoprotein; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..561
FT                   /note="Transmembrane protein 209"
FT                   /id="PRO_0000331634"
FT   TRANSMEM        28..48
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        60..80
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          120..156
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          196..233
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          250..270
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         9
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q96SK2"
FT   MOD_RES         11
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q96SK2"
FT   MOD_RES         98
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q96SK2"
FT   MOD_RES         201
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q96SK2"
FT   MOD_RES         248
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q96SK2"
FT   MOD_RES         278
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q96SK2"
FT   CARBOHYD        57
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        274
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   561 AA;  62914 MW;  C8905DE00FD62269 CRC64;
     MMQGEVSPSP SLIDRTIRMR KETESRKVVL AWGLLNVSMA GMIYTEMTGK LISTYYNVTY
     WPLWYIELAL ASLFSLNALF DFWRYFKYTV APTSLVVSPG QQTLLGLKPA VVQTTPPRDL
     AATQISPSPP SPSIQGQSVL SYSPSRSPST SPKFATSCMT GYSPQLQGLS SGGLGSYSPA
     VTYSPVSGYS KLASFSLSPS SPYPTTVGPV ESSGLRARYR SPPTAYNSPT DKEDYMTDLR
     TLDTFLRSEE EKQHRVKLGS PDSTSPSTSP TFWNYSRSVG DYAQTLKKFQ YQLACRSQAP
     CANKDEADLI SKQAAEEVWA RVTMNRQLLD HMDSWTAKFR NWISETILVP LVQEIESVST
     QMRRMGCPEL QIGEASVTSL KQAALVKAPL IPTLNAIVQY LDLTPNQEYL FERIKELSQG
     GCMSSFRWNR GGDFKGRRWD TDLPTDSAII MHVFCTYLDS RLPPHPKYPD GKTFTSQHFV
     QTPNKPDVTN ENVFCVYQSA INPPHYELIY QRHVYSLPKG RNNMFHTLLM FLYIIKTKES
     GMLGRVNLGL SGVNILWIFG E