ID   TM220_XENLA             Reviewed;         184 AA.
AC   Q4V7Q8;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2005, sequence version 1.
DT   03-AUG-2022, entry version 40.
DE   RecName: Full=Transmembrane protein 220;
GN   Name=tmem220;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Egg;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; BC097768; AAH97768.1; -; mRNA.
DR   RefSeq; NP_001090046.1; NM_001096577.1.
DR   RefSeq; XP_018090112.1; XM_018234623.1.
DR   AlphaFoldDB; Q4V7Q8; -.
DR   DNASU; 735119; -.
DR   GeneID; 735119; -.
DR   KEGG; xla:735119; -.
DR   CTD; 735119; -.
DR   Xenbase; XB-GENE-6254287; tmem220.L.
DR   OMA; LWVVVYM; -.
DR   OrthoDB; 1569116at2759; -.
DR   Proteomes; UP000186698; Chromosome 9_10L.
DR   Bgee; 735119; Expressed in egg cell and 19 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR029377; TMEM220.
DR   Pfam; PF15071; TMEM220; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..184
FT                   /note="Transmembrane protein 220"
FT                   /id="PRO_0000319426"
FT   TRANSMEM        30..50
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        54..74
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        82..102
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        121..137
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        149..169
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   184 AA;  20906 MW;  CBD97FC881542F1C CRC64;
     MEGSGTEQKG SPKCSFLTNS LLCHENRQRL WRICNFIMFG FFSLAAYVQI NDPDAEMWIV
     IYMIPAVLIL FVSIKPDITG HVIWKLLADL HSAVCAVGAI YLSGCLYFYT SKNILHEEEG
     RELSGLLIIS GWLLLCRKSH QSAIGAIRLI IAISVSTAPF FIWIYIYIDK EMRTSWPQHC
     KTVI