ID   TM230_BOVIN             Reviewed;         120 AA.
AC   Q5E975;
DT   02-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 88.
DE   RecName: Full=Transmembrane protein 230;
GN   Name=TMEM230;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX   PubMed=16305752; DOI=10.1186/1471-2164-6-166;
RA   Harhay G.P., Sonstegard T.S., Keele J.W., Heaton M.P., Clawson M.L.,
RA   Snelling W.M., Wiedmann R.T., Van Tassell C.P., Smith T.P.L.;
RT   "Characterization of 954 bovine full-CDS cDNA sequences.";
RL   BMC Genomics 6:166-166(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in trafficking and recycling of synaptic vesicles.
CC       {ECO:0000250|UniProtKB:Q96A57}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}. Golgi apparatus, trans-Golgi network
CC       {ECO:0000250|UniProtKB:Q96A57}. Cytoplasmic vesicle, secretory vesicle,
CC       synaptic vesicle {ECO:0000250|UniProtKB:Q96A57}. Early endosome
CC       {ECO:0000250|UniProtKB:Q96A57}. Recycling endosome
CC       {ECO:0000250|UniProtKB:Q96A57}. Late endosome
CC       {ECO:0000250|UniProtKB:Q96A57}. Cytoplasmic vesicle, autophagosome
CC       {ECO:0000250|UniProtKB:Q96A57}.
CC   -!- SIMILARITY: Belongs to the TMEM134/TMEM230 family. {ECO:0000305}.
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DR   EMBL; BT021045; AAX09062.1; -; mRNA.
DR   EMBL; BC109791; AAI09792.1; -; mRNA.
DR   RefSeq; NP_001014930.1; NM_001014930.3.
DR   RefSeq; XP_005214513.1; XM_005214456.3.
DR   AlphaFoldDB; Q5E975; -.
DR   STRING; 9913.ENSBTAP00000007965; -.
DR   PaxDb; Q5E975; -.
DR   PRIDE; Q5E975; -.
DR   Ensembl; ENSBTAT00000007965; ENSBTAP00000007965; ENSBTAG00000006063.
DR   GeneID; 515498; -.
DR   KEGG; bta:515498; -.
DR   CTD; 29058; -.
DR   VEuPathDB; HostDB:ENSBTAG00000006063; -.
DR   eggNOG; KOG4753; Eukaryota.
DR   GeneTree; ENSGT00390000008694; -.
DR   HOGENOM; CLU_126638_1_0_1; -.
DR   InParanoid; Q5E975; -.
DR   OMA; AYYAYYK; -.
DR   OrthoDB; 1557903at2759; -.
DR   TreeFam; TF329240; -.
DR   Proteomes; UP000009136; Chromosome 13.
DR   Bgee; ENSBTAG00000006063; Expressed in caput epididymis and 102 other tissues.
DR   GO; GO:0070161; C:anchoring junction; IEA:UniProtKB-KW.
DR   GO; GO:0005776; C:autophagosome; IEA:UniProtKB-SubCell.
DR   GO; GO:0005769; C:early endosome; ISS:UniProtKB.
DR   GO; GO:0012505; C:endomembrane system; IBA:GO_Central.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005770; C:late endosome; ISS:UniProtKB.
DR   GO; GO:0055037; C:recycling endosome; ISS:UniProtKB.
DR   GO; GO:0008021; C:synaptic vesicle; ISS:UniProtKB.
DR   GO; GO:0005802; C:trans-Golgi network; ISS:UniProtKB.
DR   GO; GO:0048489; P:synaptic vesicle transport; ISS:UniProtKB.
DR   InterPro; IPR044234; TMEM230.
DR   InterPro; IPR008590; TMEM_230/134.
DR   PANTHER; PTHR15664; PTHR15664; 1.
DR   Pfam; PF05915; TMEM_230_134; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasmic vesicle; Endosome; Golgi apparatus; Membrane; Phosphoprotein;
KW   Reference proteome; Synapse; Transmembrane; Transmembrane helix.
FT   CHAIN           1..120
FT                   /note="Transmembrane protein 230"
FT                   /id="PRO_0000233891"
FT   TRANSMEM        51..71
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        79..99
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   MOD_RES         15
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q96A57"
FT   MOD_RES         23
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q96A57"
FT   MOD_RES         24
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q96A57"
SQ   SEQUENCE   120 AA;  13158 MW;  EDD3A55329BD22D4 CRC64;
     MMPSRTNLAT GIPSSKVKYS RLSSTDDGYI DLQFKKSPPK IPYKAIALAT VLFLIGAFLI
     IIGSLLLAGY ISKGGADRAV PVLIIGILVF LPGFYHLRIA YYASKGYRGY SYDDIPDFDD