ID   TM230_CHICK             Reviewed;         120 AA.
AC   Q5ZLH4;
DT   02-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 91.
DE   RecName: Full=Transmembrane protein 230;
GN   Name=TMEM230; ORFNames=RCJMB04_6c24;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB; TISSUE=Bursa of Fabricius;
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- FUNCTION: Involved in trafficking and recycling of synaptic vesicles.
CC       {ECO:0000250|UniProtKB:Q96A57}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}. Golgi apparatus, trans-Golgi network
CC       {ECO:0000250|UniProtKB:Q96A57}. Cytoplasmic vesicle, secretory vesicle,
CC       synaptic vesicle {ECO:0000250|UniProtKB:Q96A57}. Early endosome
CC       {ECO:0000250|UniProtKB:Q96A57}. Recycling endosome
CC       {ECO:0000250|UniProtKB:Q96A57}. Late endosome
CC       {ECO:0000250|UniProtKB:Q96A57}. Cytoplasmic vesicle, autophagosome
CC       {ECO:0000250|UniProtKB:Q96A57}.
CC   -!- SIMILARITY: Belongs to the TMEM134/TMEM230 family. {ECO:0000305}.
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DR   EMBL; AJ719760; CAG31419.1; -; mRNA.
DR   RefSeq; NP_001007878.1; NM_001007877.1.
DR   RefSeq; XP_015152790.1; XM_015297304.1.
DR   AlphaFoldDB; Q5ZLH4; -.
DR   STRING; 9031.ENSGALP00000000226; -.
DR   PaxDb; Q5ZLH4; -.
DR   Ensembl; ENSGALT00000072760; ENSGALP00000046386; ENSGALG00000036876.
DR   Ensembl; ENSGALT00000087311; ENSGALP00000059662; ENSGALG00000036876.
DR   Ensembl; ENSGALT00000093446; ENSGALP00000069637; ENSGALG00000036876.
DR   GeneID; 419518; -.
DR   KEGG; gga:419518; -.
DR   CTD; 29058; -.
DR   VEuPathDB; HostDB:geneid_419518; -.
DR   eggNOG; KOG4753; Eukaryota.
DR   GeneTree; ENSGT00390000008694; -.
DR   HOGENOM; CLU_126638_1_0_1; -.
DR   InParanoid; Q5ZLH4; -.
DR   OMA; AYYAYYK; -.
DR   OrthoDB; 1557903at2759; -.
DR   PhylomeDB; Q5ZLH4; -.
DR   TreeFam; TF329240; -.
DR   PRO; PR:Q5ZLH4; -.
DR   Proteomes; UP000000539; Chromosome 22.
DR   Bgee; ENSGALG00000036876; Expressed in liver and 12 other tissues.
DR   GO; GO:0070161; C:anchoring junction; IEA:UniProtKB-KW.
DR   GO; GO:0005776; C:autophagosome; IEA:UniProtKB-SubCell.
DR   GO; GO:0005769; C:early endosome; ISS:UniProtKB.
DR   GO; GO:0012505; C:endomembrane system; IBA:GO_Central.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:Ensembl.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005770; C:late endosome; ISS:UniProtKB.
DR   GO; GO:0055037; C:recycling endosome; ISS:UniProtKB.
DR   GO; GO:0008021; C:synaptic vesicle; ISS:UniProtKB.
DR   GO; GO:0005802; C:trans-Golgi network; ISS:UniProtKB.
DR   GO; GO:0048489; P:synaptic vesicle transport; ISS:UniProtKB.
DR   InterPro; IPR044234; TMEM230.
DR   InterPro; IPR008590; TMEM_230/134.
DR   PANTHER; PTHR15664; PTHR15664; 1.
DR   Pfam; PF05915; TMEM_230_134; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasmic vesicle; Endosome; Golgi apparatus; Membrane;
KW   Reference proteome; Synapse; Transmembrane; Transmembrane helix.
FT   CHAIN           1..120
FT                   /note="Transmembrane protein 230"
FT                   /id="PRO_0000233896"
FT   TRANSMEM        46..66
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        79..99
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   120 AA;  13175 MW;  26B381EA43B1F57F CRC64;
     MMPSRTNLSA GIPSSKVKYS KLASTDDGYI DLQFKKSPPK IPYKAIALAV VLFMIGTFLI
     IIGALLLAGY ISKGGTDRAI PVLIIGILVF LPGFYHLRIA YYASKGYRGY SYDDIPDFDD