ID   TM230_PONAB             Reviewed;         120 AA.
AC   Q5R8X3;
DT   02-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   03-AUG-2022, entry version 58.
DE   RecName: Full=Transmembrane protein 230;
GN   Name=TMEM230;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain cortex;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in trafficking and recycling of synaptic vesicles.
CC       {ECO:0000250|UniProtKB:Q96A57}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}. Golgi apparatus, trans-Golgi network
CC       {ECO:0000250|UniProtKB:Q96A57}. Cytoplasmic vesicle, secretory vesicle,
CC       synaptic vesicle {ECO:0000250|UniProtKB:Q96A57}. Early endosome
CC       {ECO:0000250|UniProtKB:Q96A57}. Recycling endosome
CC       {ECO:0000250|UniProtKB:Q96A57}. Late endosome
CC       {ECO:0000250|UniProtKB:Q96A57}. Cytoplasmic vesicle, autophagosome
CC       {ECO:0000250|UniProtKB:Q96A57}.
CC   -!- SIMILARITY: Belongs to the TMEM134/TMEM230 family. {ECO:0000305}.
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DR   EMBL; CR859625; CAH91787.1; -; mRNA.
DR   RefSeq; NP_001126037.1; NM_001132565.1.
DR   AlphaFoldDB; Q5R8X3; -.
DR   STRING; 9601.ENSPPYP00000012060; -.
DR   GeneID; 100172986; -.
DR   KEGG; pon:100172986; -.
DR   CTD; 29058; -.
DR   eggNOG; KOG4753; Eukaryota.
DR   InParanoid; Q5R8X3; -.
DR   OrthoDB; 1357985at2759; -.
DR   Proteomes; UP000001595; Unplaced.
DR   GO; GO:0070161; C:anchoring junction; IEA:UniProtKB-KW.
DR   GO; GO:0005776; C:autophagosome; IEA:UniProtKB-SubCell.
DR   GO; GO:0005769; C:early endosome; ISS:UniProtKB.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005770; C:late endosome; ISS:UniProtKB.
DR   GO; GO:0055037; C:recycling endosome; ISS:UniProtKB.
DR   GO; GO:0008021; C:synaptic vesicle; ISS:UniProtKB.
DR   GO; GO:0005802; C:trans-Golgi network; ISS:UniProtKB.
DR   GO; GO:0048489; P:synaptic vesicle transport; ISS:UniProtKB.
DR   InterPro; IPR044234; TMEM230.
DR   InterPro; IPR008590; TMEM_230/134.
DR   PANTHER; PTHR15664; PTHR15664; 1.
DR   Pfam; PF05915; TMEM_230_134; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasmic vesicle; Endosome; Golgi apparatus; Membrane; Phosphoprotein;
KW   Reference proteome; Synapse; Transmembrane; Transmembrane helix.
FT   CHAIN           1..120
FT                   /note="Transmembrane protein 230"
FT                   /id="PRO_0000233894"
FT   TRANSMEM        46..66
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        79..99
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   MOD_RES         15
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q96A57"
FT   MOD_RES         23
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q96A57"
FT   MOD_RES         24
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q96A57"
SQ   SEQUENCE   120 AA;  13160 MW;  148C12C53317DD7E CRC64;
     MMPSRTNLAT GIPSSKVKYS RLSSTDDGYI DLQFKKTPPK IPYKAIALAT GLFLIGAFLI
     IIGSLLLSGY ISKGGADRAI PVLIIGILVF LPGFYHLRIA YYASKGYRGY SYDDIPDFDD