ID   TM234_PONAB             Reviewed;         166 AA.
AC   Q5RBQ9; Q5R4K7;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   25-MAY-2022, entry version 48.
DE   RecName: Full=Transmembrane protein 234;
GN   Name=TMEM234;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC   TISSUE=Brain cortex, and Kidney;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=1;
CC         IsoId=Q5RBQ9-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=Q5RBQ9-2; Sequence=VSP_028110, VSP_028111, VSP_028112;
CC   -!- SIMILARITY: Belongs to the TMEM234 family. {ECO:0000305}.
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DR   EMBL; CR858579; CAH90801.1; -; mRNA.
DR   EMBL; CR861239; CAH93309.1; ALT_TERM; mRNA.
DR   RefSeq; NP_001128785.1; NM_001135313.1. [Q5RBQ9-1]
DR   AlphaFoldDB; Q5RBQ9; -.
DR   STRING; 9601.ENSPPYP00000001843; -.
DR   GeneID; 100189688; -.
DR   KEGG; pon:100189688; -.
DR   CTD; 56063; -.
DR   eggNOG; KOG4831; Eukaryota.
DR   InParanoid; Q5RBQ9; -.
DR   OrthoDB; 1343300at2759; -.
DR   Proteomes; UP000001595; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR018908; TMEM234.
DR   PANTHER; PTHR28668; PTHR28668; 1.
DR   Pfam; PF10639; TMEM234; 1.
PE   2: Evidence at transcript level;
KW   Alternative splicing; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..166
FT                   /note="Transmembrane protein 234"
FT                   /id="PRO_0000304698"
FT   TRANSMEM        1..21
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        82..102
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        112..132
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   VAR_SEQ         110..111
FT                   /note="Missing (in isoform 2)"
FT                   /evidence="ECO:0000303|Ref.1"
FT                   /id="VSP_028110"
FT   VAR_SEQ         130..133
FT                   /note="WQVP -> LSSC (in isoform 2)"
FT                   /evidence="ECO:0000303|Ref.1"
FT                   /id="VSP_028111"
FT   VAR_SEQ         134..166
FT                   /note="Missing (in isoform 2)"
FT                   /evidence="ECO:0000303|Ref.1"
FT                   /id="VSP_028112"
FT   CONFLICT        49
FT                   /note="Q -> K (in Ref. 1; CAH93309)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   166 AA;  17974 MW;  E509795C71A7623A CRC64;
     MAASLGQVLA LVLVAALWGG TQPLLKRASA ALQRVREPTW VRQLLQEMQT LFLNTEYLMP
     FLLNQCGSLL YYLTLASTDL TLAVPICNSL AIIFTLIVGK ALGEDIGGKR AVAGMVLTVI
     GISLCITSSW QVPWTAELQL HGKGQLQTLS QKCKREASGA QSERFG