ID   TM236_RABIT             Reviewed;         351 AA.
AC   Q05005;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2005, sequence version 2.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=Transmembrane protein 236;
DE   AltName: Full=Brush border protein AdRab-C;
GN   Name=TMEM236;
OS   Oryctolagus cuniculus (Rabbit).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus.
OX   NCBI_TaxID=9986;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, AND DEVELOPMENTAL STAGE.
RX   PubMed=8509424; DOI=10.1016/s0021-9258(18)31471-6;
RA   Boll W., Schmid-Chanda T., Semenza G., Mantei N.;
RT   "Messenger RNAs expressed in intestine of adult but not baby rabbits.
RT   Isolation of cognate cDNAs and characterization of a novel brush border
RT   protein with esterase and phospholipase activity.";
RL   J. Biol. Chem. 268:12901-12911(1993).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- TISSUE SPECIFICITY: Intestine. {ECO:0000269|PubMed:8509424}.
CC   -!- DEVELOPMENTAL STAGE: Expressed in the intestine of adult but not baby
CC       rabbits. {ECO:0000269|PubMed:8509424}.
CC   -!- SIMILARITY: Belongs to the TMEM236 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAA78304.1; Type=Frameshift; Evidence={ECO:0000305};
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DR   EMBL; Z12842; CAA78304.1; ALT_FRAME; mRNA.
DR   PIR; C45665; C45665.
DR   AlphaFoldDB; Q05005; -.
DR   STRING; 9986.ENSOCUP00000002812; -.
DR   eggNOG; ENOG502QVFM; Eukaryota.
DR   InParanoid; Q05005; -.
DR   Proteomes; UP000001811; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR020394; Uncharacterised_FAM23-like_TM.
DR   PANTHER; PTHR31453; PTHR31453; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..351
FT                   /note="Transmembrane protein 236"
FT                   /id="PRO_0000186717"
FT   TRANSMEM        9..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        49..69
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        88..108
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        121..141
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        264..284
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        301..321
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        116
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   351 AA;  39814 MW;  A5D1DC12B351B1C8 CRC64;
     MASGRLIKLV IFELLEFAAF SIPTLVIMEQ FATAYQRTRN ASEKTHYWLI VSCSIAYVAV
     VSLLIWVPVK VLLHKKRHLY KKIKGWRPVM MMCVVLTTLP SFIFSIAVTE VQKTINTTVD
     VLPDTLPDLP VSLVISSLII TDIIEKLRFH PIRGYQKSNE DKHIHTSSLQ QVRTVTEQVR
     QNGENAASPC AASPSETWQP PGALTHSAVP MFAGPQEPFF GSGILKTMSR RDVRAEIFLW
     SFLLWSDTIE MVRVAGHPNV YKTNWLYPVY LFSFISLLRI IFTPQNPLLS CLGILLQDLP
     FVFVRLSLII ALGTITPVLG LCKNVLVTLS YVYFNFLTRF RAFSNFELSP F