ID   TM247_BOVIN             Reviewed;         217 AA.
AC   Q2YDG1;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   08-APR-2008, sequence version 2.
DT   03-AUG-2022, entry version 73.
DE   RecName: Full=Transmembrane protein 247;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Hereford;
RX   PubMed=19390049; DOI=10.1126/science.1169588;
RG   The bovine genome sequencing and analysis consortium;
RT   "The genome sequence of taurine cattle: a window to ruminant biology and
RT   evolution.";
RL   Science 324:522-528(2009).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAI10241.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AAFC03016455; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BC110240; AAI10241.1; ALT_INIT; mRNA.
DR   RefSeq; NP_001070537.2; NM_001077069.1.
DR   AlphaFoldDB; Q2YDG1; -.
DR   SMR; Q2YDG1; -.
DR   STRING; 9913.ENSBTAP00000005367; -.
DR   PaxDb; Q2YDG1; -.
DR   GeneID; 768009; -.
DR   KEGG; bta:768009; -.
DR   CTD; 388946; -.
DR   eggNOG; ENOG502SRZ8; Eukaryota.
DR   HOGENOM; CLU_112717_0_0_1; -.
DR   InParanoid; Q2YDG1; -.
DR   OrthoDB; 1081739at2759; -.
DR   TreeFam; TF337834; -.
DR   Proteomes; UP000009136; Unplaced.
DR   GO; GO:0005783; C:endoplasmic reticulum; IBA:GO_Central.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR029200; TMEM247.
DR   PANTHER; PTHR36691; PTHR36691; 1.
DR   Pfam; PF15444; TMEM247; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..217
FT                   /note="Transmembrane protein 247"
FT                   /id="PRO_0000328812"
FT   TRANSMEM        165..185
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        192..212
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..87
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          109..154
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   217 AA;  24443 MW;  CD8B05FAFE393950 CRC64;
     MATEDREMME GRGAGESCPT FPKMAPDDPM SEGKPRASLP QEADTPKPDS SYDYLEEMET
     CEDGGCPGPP KVLSSKAGPA TTKGQAGDGL ELAELPSVPA TAAPGSPVRE RDAEMELEKV
     RMEFELKRLK YLHEENERQR QHEEVMEQLQ QQATPRLFSG GLQDLLLPQN QFAMFLYCFI
     FIHIIYVTKE MIFFLFSKHY LFCIAAILLC LIKTLWS