ID   TM251_BOVIN             Reviewed;         163 AA.
AC   Q2HJ69;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2006, sequence version 1.
DT   03-AUG-2022, entry version 73.
DE   RecName: Full=Transmembrane protein 251;
GN   Name=TMEM251;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Uterus;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}. Golgi apparatus {ECO:0000250|UniProtKB:Q8N6I4}.
CC   -!- SIMILARITY: Belongs to the TMEM251 family. {ECO:0000305}.
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DR   EMBL; BC113282; AAI13283.1; -; mRNA.
DR   RefSeq; NP_001070600.1; NM_001077132.1.
DR   RefSeq; XP_010815578.1; XM_010817276.2.
DR   AlphaFoldDB; Q2HJ69; -.
DR   STRING; 9913.ENSBTAP00000042633; -.
DR   PaxDb; Q2HJ69; -.
DR   Ensembl; ENSBTAT00000045223; ENSBTAP00000042633; ENSBTAG00000031885.
DR   GeneID; 768076; -.
DR   KEGG; bta:768076; -.
DR   CTD; 26175; -.
DR   VEuPathDB; HostDB:ENSBTAG00000031885; -.
DR   VGNC; VGNC:36060; TMEM251.
DR   eggNOG; ENOG502RY2J; Eukaryota.
DR   GeneTree; ENSGT00390000007473; -.
DR   HOGENOM; CLU_133007_0_0_1; -.
DR   InParanoid; Q2HJ69; -.
DR   OMA; AYYIFEV; -.
DR   OrthoDB; 1528152at2759; -.
DR   TreeFam; TF332722; -.
DR   Proteomes; UP000009136; Chromosome 21.
DR   Bgee; ENSBTAG00000031885; Expressed in oocyte and 105 other tissues.
DR   GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR028024; TMEM251.
DR   PANTHER; PTHR31925; PTHR31925; 1.
DR   Pfam; PF15190; TMEM251; 1.
PE   2: Evidence at transcript level;
KW   Golgi apparatus; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..163
FT                   /note="Transmembrane protein 251"
FT                   /id="PRO_0000359884"
FT   TRANSMEM        40..60
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        98..118
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   163 AA;  18880 MW;  81385E757C412F09 CRC64;
     MPKPPDYSEL SDSLTLAVGT GRFSGPLHRA WRMMNFRQRM GWIGVGLYLL ASAAAFYYVF
     EINETYNRLA LEHIQQHPEE PLEGTTWTHS LKTRLLSLPF WFWTVVFLIP YLQMFLFLYS
     CTRADPKTVG YCIIPICLAV ICNRHQAFVK ASNQISRLQL IDT