ID   TM251_CHICK             Reviewed;         131 AA.
AC   Q5ZLR7;
DT   19-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 2.
DT   03-AUG-2022, entry version 86.
DE   RecName: Full=Transmembrane protein 251;
GN   Name=TMEM251; ORFNames=RCJMB04_5b13;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB; TISSUE=Bursa of Fabricius;
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}. Golgi apparatus {ECO:0000250|UniProtKB:Q8N6I4}.
CC   -!- SIMILARITY: Belongs to the TMEM251 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAG31326.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AJ719667; CAG31326.1; ALT_INIT; mRNA.
DR   RefSeq; NP_001073200.1; NM_001079732.1.
DR   AlphaFoldDB; Q5ZLR7; -.
DR   STRING; 9031.ENSGALP00000028021; -.
DR   PaxDb; Q5ZLR7; -.
DR   Ensembl; ENSGALT00000107325; ENSGALP00000066120; ENSGALG00000051040.
DR   GeneID; 423422; -.
DR   KEGG; gga:423422; -.
DR   CTD; 26175; -.
DR   VEuPathDB; HostDB:geneid_423422; -.
DR   eggNOG; ENOG502RY2J; Eukaryota.
DR   GeneTree; ENSGT00390000007473; -.
DR   HOGENOM; CLU_133007_0_0_1; -.
DR   InParanoid; Q5ZLR7; -.
DR   OMA; AYYIFEV; -.
DR   OrthoDB; 1528152at2759; -.
DR   PhylomeDB; Q5ZLR7; -.
DR   TreeFam; TF332722; -.
DR   PRO; PR:Q5ZLR7; -.
DR   Proteomes; UP000000539; Chromosome 5.
DR   Bgee; ENSGALG00000051040; Expressed in granulocyte and 14 other tissues.
DR   GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR028024; TMEM251.
DR   PANTHER; PTHR31925; PTHR31925; 1.
DR   Pfam; PF15190; TMEM251; 1.
PE   2: Evidence at transcript level;
KW   Golgi apparatus; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..131
FT                   /note="Transmembrane protein 251"
FT                   /id="PRO_0000089915"
FT   TRANSMEM        8..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        66..86
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   131 AA;  15363 MW;  8594B5E0A35F8D04 CRC64;
     MMNFRQRMGW IGVGLYLLAS AAAFYYVFEI NETYNKLALE HIQQHPQEPQ EGTTWTHSLK
     VRLLSLPFWL WTIIFLIPYL QMFLFLYSCT RADPKTVGYC IIPICLAVIC NRHQTFVKAS
     NQISRLQLID T