ID   TM252_PONAB             Reviewed;         170 AA.
AC   Q5RF75;
DT   05-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   25-MAY-2022, entry version 52.
DE   RecName: Full=Transmembrane protein 252;
GN   Name=TMEM252;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; CR857286; CAH89582.1; -; mRNA.
DR   RefSeq; NP_001127170.1; NM_001133698.2.
DR   AlphaFoldDB; Q5RF75; -.
DR   STRING; 9601.ENSPPYP00000021582; -.
DR   GeneID; 100174222; -.
DR   KEGG; pon:100174222; -.
DR   CTD; 169693; -.
DR   eggNOG; ENOG502S6KQ; Eukaryota.
DR   InParanoid; Q5RF75; -.
DR   OrthoDB; 1607376at2759; -.
DR   Proteomes; UP000001595; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR031363; TMEM252.
DR   PANTHER; PTHR35682; PTHR35682; 1.
DR   Pfam; PF15664; TMEM252; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..170
FT                   /note="Transmembrane protein 252"
FT                   /id="PRO_0000089709"
FT   TRANSMEM        8..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        40..60
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          112..147
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   170 AA;  18723 MW;  D3171C137A3F0973 CRC64;
     MQNRTGLILC ALALLMGFLM VCLGAFFISW GSIFDCQGSL IAAYLLLPLG FVILLSGIFW
     SNYRQVTESK GVLRHMLRQH LAHGALSVAT VDRPDFYPPA YEESLEVEKQ SCPAEREASG
     IPPPLYTETG LEFQDGNDSH PEAPPSYRES IASLVVTAIS EDAQRRGQEC