ID   TM252_RAT               Reviewed;         185 AA.
AC   Q6AXS2;
DT   05-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2004, sequence version 1.
DT   03-AUG-2022, entry version 92.
DE   RecName: Full=Transmembrane protein 252;
GN   Name=Tmem252;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; BC079347; AAH79347.1; -; mRNA.
DR   RefSeq; NP_001007739.1; NM_001007738.1.
DR   AlphaFoldDB; Q6AXS2; -.
DR   SMR; Q6AXS2; -.
DR   STRING; 10116.ENSRNOP00000030850; -.
DR   PaxDb; Q6AXS2; -.
DR   Ensembl; ENSRNOT00000035123; ENSRNOP00000030850; ENSRNOG00000025476.
DR   GeneID; 361744; -.
DR   KEGG; rno:361744; -.
DR   UCSC; RGD:1359349; rat.
DR   CTD; 169693; -.
DR   RGD; 1359349; Tmem252.
DR   eggNOG; ENOG502S6KQ; Eukaryota.
DR   GeneTree; ENSGT00390000005250; -.
DR   HOGENOM; CLU_117690_0_0_1; -.
DR   InParanoid; Q6AXS2; -.
DR   OMA; LYTEMGL; -.
DR   OrthoDB; 1607376at2759; -.
DR   PhylomeDB; Q6AXS2; -.
DR   TreeFam; TF337811; -.
DR   PRO; PR:Q6AXS2; -.
DR   Proteomes; UP000002494; Chromosome 1.
DR   Bgee; ENSRNOG00000025476; Expressed in kidney and 18 other tissues.
DR   Genevisible; Q6AXS2; RN.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR031363; TMEM252.
DR   PANTHER; PTHR35682; PTHR35682; 1.
DR   Pfam; PF15664; TMEM252; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..185
FT                   /note="Transmembrane protein 252"
FT                   /id="PRO_0000089710"
FT   TRANSMEM        8..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        39..59
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          125..149
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   185 AA;  20193 MW;  983DC89370797E6A CRC64;
     MQNRTGLVLC ALSLLTGFLM ICLGGFFISS SSSHSHRNLV VAYVLLPLGF VILLSGIFWG
     TYRQANDNKE MFNHVLRQHL AFQDLPLATV DRPDFYPPAY EESLDVEKQA CSAGRGLLGF
     PPPLYTETSL EPQDKDKNDP QPEAPPPYPE NIAVAAATVK TQDAEEPSTV LKAGAVLQLS
     ELASC