ID   TM254_BOVIN             Reviewed;         124 AA.
AC   Q0D2G3;
DT   09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   17-OCT-2006, sequence version 1.
DT   03-AUG-2022, entry version 72.
DE   RecName: Full=Transmembrane protein 254;
GN   Name=TMEM254;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Hypothalamus;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; BC114852; AAI14853.1; -; mRNA.
DR   RefSeq; NP_001068696.1; NM_001075228.2.
DR   AlphaFoldDB; Q0D2G3; -.
DR   STRING; 9913.ENSBTAP00000002166; -.
DR   PaxDb; Q0D2G3; -.
DR   PRIDE; Q0D2G3; -.
DR   Ensembl; ENSBTAT00000002166; ENSBTAP00000002166; ENSBTAG00000001656.
DR   GeneID; 505854; -.
DR   KEGG; bta:505854; -.
DR   CTD; 80195; -.
DR   VEuPathDB; HostDB:ENSBTAG00000001656; -.
DR   VGNC; VGNC:36063; TMEM254.
DR   eggNOG; ENOG502S4F5; Eukaryota.
DR   GeneTree; ENSGT00390000016042; -.
DR   HOGENOM; CLU_150378_0_0_1; -.
DR   InParanoid; Q0D2G3; -.
DR   OMA; LLYKGWW; -.
DR   OrthoDB; 1399874at2759; -.
DR   TreeFam; TF328617; -.
DR   Proteomes; UP000009136; Chromosome 28.
DR   Bgee; ENSBTAG00000001656; Expressed in diaphragm and 104 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR028110; TMEM254.
DR   PANTHER; PTHR34104; PTHR34104; 1.
DR   Pfam; PF14934; DUF4499; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..124
FT                   /note="Transmembrane protein 254"
FT                   /id="PRO_0000271443"
FT   TRANSMEM        16..36
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        62..82
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        96..116
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   124 AA;  14724 MW;  8218A6DAC79EEB1A CRC64;
     MGKARGDEAY FQRSSLFWVT IIILSFGYYT WVIFWPESIP YQSLGPLGPF TQYLLKHHHT
     LVHAWYWLAW MIHVGESLYA IVLCKSKGIT NTWTQLLWFL QTFLFGLASL YYLIAFRPKH
     QKQT