ID   TM254_PONAB             Reviewed;         123 AA.
AC   Q5R9A6;
DT   19-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   03-AUG-2022, entry version 63.
DE   RecName: Full=Transmembrane protein 254;
GN   Name=TMEM254;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain cortex;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CR859483; CAH91654.1; -; mRNA.
DR   RefSeq; NP_001127449.1; NM_001133977.1.
DR   AlphaFoldDB; Q5R9A6; -.
DR   STRING; 9601.ENSPPYP00000002668; -.
DR   GeneID; 100174520; -.
DR   KEGG; pon:100174520; -.
DR   CTD; 80195; -.
DR   eggNOG; ENOG502S4F5; Eukaryota.
DR   HOGENOM; CLU_150378_0_0_1; -.
DR   InParanoid; Q5R9A6; -.
DR   OMA; LLYKGWW; -.
DR   OrthoDB; 1399874at2759; -.
DR   TreeFam; TF328617; -.
DR   Proteomes; UP000001595; Chromosome 10.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR028110; TMEM254.
DR   PANTHER; PTHR34104; PTHR34104; 1.
DR   Pfam; PF14934; DUF4499; 1.
PE   2: Evidence at transcript level;
KW   Acetylation; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250|UniProtKB:Q8TBM7"
FT   CHAIN           2..123
FT                   /note="Transmembrane protein 254"
FT                   /id="PRO_0000089798"
FT   TRANSMEM        15..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        61..81
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        95..115
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   MOD_RES         2
FT                   /note="N-acetylalanine"
FT                   /evidence="ECO:0000250|UniProtKB:Q8TBM7"
SQ   SEQUENCE   123 AA;  14114 MW;  56AB163D87C48574 CRC64;
     MATAAGAAYF QRGSLFWFTV ITLSFGYYTW VVFWPQSIPY QNLGPLGPFT QYLVDHHHTL
     LCNGYWLAWL IHVGESLYAI VLCKHKGITS GRAQLLWFLQ TFFFGIASLT ILIAYKGKRQ
     KQT