ID   TM254_RAT               Reviewed;         123 AA.
AC   Q5U220;
DT   19-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   07-DEC-2004, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=Transmembrane protein 254;
GN   Name=Tmem254;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Ovary;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; BC086323; AAH86323.1; -; mRNA.
DR   RefSeq; NP_001008298.1; NM_001008297.1.
DR   AlphaFoldDB; Q5U220; -.
DR   STRING; 10116.ENSRNOP00000015011; -.
DR   PhosphoSitePlus; Q5U220; -.
DR   PaxDb; Q5U220; -.
DR   PRIDE; Q5U220; -.
DR   Ensembl; ENSRNOT00000015011; ENSRNOP00000015011; ENSRNOG00000011276.
DR   GeneID; 290529; -.
DR   KEGG; rno:290529; -.
DR   UCSC; RGD:1305689; rat.
DR   CTD; 80195; -.
DR   RGD; 1305689; Tmem254.
DR   eggNOG; ENOG502S4F5; Eukaryota.
DR   GeneTree; ENSGT00390000016042; -.
DR   HOGENOM; CLU_150378_0_0_1; -.
DR   InParanoid; Q5U220; -.
DR   OMA; LLYKGWW; -.
DR   PRO; PR:Q5U220; -.
DR   Proteomes; UP000002494; Chromosome 16.
DR   Bgee; ENSRNOG00000011276; Expressed in stomach and 20 other tissues.
DR   ExpressionAtlas; Q5U220; baseline and differential.
DR   Genevisible; Q5U220; RN.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR028110; TMEM254.
DR   PANTHER; PTHR34104; PTHR34104; 1.
DR   Pfam; PF14934; DUF4499; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..123
FT                   /note="Transmembrane protein 254"
FT                   /id="PRO_0000089799"
FT   TRANSMEM        15..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        63..83
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        95..115
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   123 AA;  14290 MW;  281B4D7C05B4C487 CRC64;
     MGTATGASYF QRGSLFWFTV IAVSFSYYTW VVFWPQSIPY QSLGPLGPFT KYLVDHYHTL
     LRNGYWLAWL VHVGESLYAL VLCRRKGITD SQAQLLWFLQ TFLFGVASLS ILFAYRPKHQ
     KHN