ID   TM256_BUFGR             Reviewed;         114 AA.
AC   A4K526;
DT   10-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2007, sequence version 1.
DT   25-MAY-2022, entry version 22.
DE   RecName: Full=Transmembrane protein 256 homolog;
DE   Flags: Precursor;
OS   Bufo gargarizans (Asian toad) (Bufo bufo gargarizans).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Neobatrachia; Hyloidea; Bufonidae; Bufo.
OX   NCBI_TaxID=30331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Venom gland;
RA   Deng W.;
RT   "Identification of venom proteins from the Chinese toad, Bufo bufo
RT   gargarizans, using an integrated proteomic and transcriptomic strategy.";
RL   Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TMEM256 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; DQ437107; ABD75374.1; -; mRNA.
DR   AlphaFoldDB; A4K526; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR006696; DUF423.
DR   PANTHER; PTHR43461; PTHR43461; 1.
DR   Pfam; PF04241; DUF423; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Signal; Transmembrane; Transmembrane helix.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000255"
FT   CHAIN           26..114
FT                   /note="Transmembrane protein 256 homolog"
FT                   /id="PRO_0000294145"
FT   TOPO_DOM        26..64
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        65..85
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        86..93
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        94..114
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   114 AA;  12142 MW;  BB7EFEB7AC074E46 CRC64;
     MAAGRVWGRL GAVSGALAVT AGAYGAHGFR RSDRDEYLKE LFETGNRYHF LHSLALLAVP
     HCRRPLLAGS LLTSGIVLFS GTFYYQALSG DPTLTKAAPY GGTLLILGWA AMAL