TM256_DANRE
ID TM256_DANRE Reviewed; 114 AA.
AC Q568J8;
DT 15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 10-MAY-2005, sequence version 1.
DT 03-AUG-2022, entry version 63.
DE RecName: Full=Transmembrane protein 256;
DE Flags: Precursor;
GN Name=tmem256; ORFNames=zgc:110256;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Ovary;
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the TMEM256 family. {ECO:0000305}.
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DR EMBL; BC092829; AAH92829.1; -; mRNA.
DR RefSeq; NP_001017620.1; NM_001017620.1.
DR AlphaFoldDB; Q568J8; -.
DR STRING; 7955.ENSDARP00000056789; -.
DR PaxDb; Q568J8; -.
DR GeneID; 550283; -.
DR KEGG; dre:550283; -.
DR CTD; 254863; -.
DR ZFIN; ZDB-GENE-050417-92; tmem256.
DR eggNOG; KOG3472; Eukaryota.
DR InParanoid; Q568J8; -.
DR OrthoDB; 1632823at2759; -.
DR PhylomeDB; Q568J8; -.
DR PRO; PR:Q568J8; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Unplaced.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR InterPro; IPR006696; DUF423.
DR PANTHER; PTHR43461; PTHR43461; 1.
DR Pfam; PF04241; DUF423; 1.
PE 3: Inferred from homology;
KW Membrane; Reference proteome; Signal; Transmembrane; Transmembrane helix.
FT SIGNAL 1..25
FT /evidence="ECO:0000255"
FT CHAIN 26..114
FT /note="Transmembrane protein 256"
FT /id="PRO_0000287172"
FT TOPO_DOM 26..64
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 65..85
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 86..93
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 94..114
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 114 AA; 11954 MW; 26AD03D19EFA4C99 CRC64;
MNAASLVQRV AGISGALAVA AGAYGAHGFR RSEASDYQRE LFDTANKYHF YHSLALLGAA
RCRKPALAGV ILLTGMGCFC GPLYHQPLTN DPSFSKLAPI GGSLLIVGWA AMAL