TM267_MOUSE
ID TM267_MOUSE Reviewed; 215 AA.
AC Q8VDR5; Q3SYJ5;
DT 03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 25-MAY-2022, entry version 103.
DE RecName: Full=Transmembrane protein 267 {ECO:0000312|MGI:MGI:3648543};
GN Name=Tmem267 {ECO:0000312|MGI:MGI:3648543}; Synonyms=Gm7120;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Thymus;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=FVB/N-3; TISSUE=Mammary tumor, and Olfactory epithelium;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
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DR EMBL; AK050607; BAC34338.1; -; mRNA.
DR EMBL; BC021422; AAH21422.1; -; mRNA.
DR EMBL; BC103784; AAI03785.1; -; mRNA.
DR CCDS; CCDS56899.1; -.
DR RefSeq; NP_001034333.2; NM_001039244.3.
DR RefSeq; NP_001171137.1; NM_001177666.1.
DR AlphaFoldDB; Q8VDR5; -.
DR STRING; 10090.ENSMUSP00000135685; -.
DR PaxDb; Q8VDR5; -.
DR PRIDE; Q8VDR5; -.
DR ProteomicsDB; 259108; -.
DR GeneID; 633640; -.
DR KEGG; mmu:633640; -.
DR CTD; 64417; -.
DR MGI; MGI:3648543; Tmem267.
DR eggNOG; ENOG502QQ1U; Eukaryota.
DR InParanoid; Q8VDR5; -.
DR OrthoDB; 1326580at2759; -.
DR PhylomeDB; Q8VDR5; -.
DR BioGRID-ORCS; 633640; 4 hits in 18 CRISPR screens.
DR ChiTaRS; Tmem267; mouse.
DR PRO; PR:Q8VDR5; -.
DR Proteomes; UP000000589; Unplaced.
DR RNAct; Q8VDR5; protein.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR026572; TMEM267.
DR PANTHER; PTHR13628; PTHR13628; 1.
PE 2: Evidence at transcript level;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..215
FT /note="Transmembrane protein 267"
FT /id="PRO_0000281922"
FT TRANSMEM 77..97
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 114..134
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 178..198
FT /note="Helical"
FT /evidence="ECO:0000255"
FT CONFLICT 36
FT /note="L -> F (in Ref. 2; AAI03785)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 215 AA; 24152 MW; 0B2288E0B3C2FE3F CRC64;
MASKVEKTHA LPPCCSTESL ISSIGLGIFC LVADRLLRFP IIQHNDWLRA ISDNIVHGVI
GMWSWAVVTG IRKKSDFGEV LLAGFLASVI DVDHFFQARS LSLQAALTLP RRPFLHCSTV
IPIAVLSVKL AVHLFKLRDS WRFLPWMILV SWTSHHIRDG IRHGLWICPF GKTPPLPSSF
YVISTLSLPH LCSFLMYLTG TRQTVSSKYG MRIDV
