ID   TM268_BOVIN             Reviewed;         344 AA.
AC   Q5EA48; A2VE64;
DT   06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=Transmembrane protein 268;
GN   Name=TMEM268;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX   PubMed=16305752; DOI=10.1186/1471-2164-6-166;
RA   Harhay G.P., Sonstegard T.S., Keele J.W., Heaton M.P., Clawson M.L.,
RA   Snelling W.M., Wiedmann R.T., Van Tassell C.P., Smith T.P.L.;
RT   "Characterization of 954 bovine full-CDS cDNA sequences.";
RL   BMC Genomics 6:166-166(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Thymus;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; BT020721; AAX08738.1; -; mRNA.
DR   EMBL; BC133593; AAI33594.1; -; mRNA.
DR   RefSeq; NP_001019732.1; NM_001024561.2.
DR   RefSeq; XP_005210596.1; XM_005210539.3.
DR   RefSeq; XP_005210597.1; XM_005210540.3.
DR   RefSeq; XP_005210598.1; XM_005210541.3.
DR   RefSeq; XP_015328176.1; XM_015472690.1.
DR   AlphaFoldDB; Q5EA48; -.
DR   PaxDb; Q5EA48; -.
DR   PRIDE; Q5EA48; -.
DR   GeneID; 535122; -.
DR   KEGG; bta:535122; -.
DR   CTD; 203197; -.
DR   eggNOG; ENOG502R635; Eukaryota.
DR   HOGENOM; CLU_067585_1_0_1; -.
DR   InParanoid; Q5EA48; -.
DR   OrthoDB; 868229at2759; -.
DR   TreeFam; TF353168; -.
DR   Proteomes; UP000009136; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR028054; DUF4481.
DR   PANTHER; PTHR31193; PTHR31193; 1.
DR   Pfam; PF14800; DUF4481; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..344
FT                   /note="Transmembrane protein 268"
FT                   /id="PRO_0000279424"
FT   TRANSMEM        106..126
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        133..153
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..31
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          244..266
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   344 AA;  38017 MW;  15641B51C24E885D CRC64;
     MACEPQMDPG GAAGPLPTSS PGWSPLPGGS PPGWGQELRS GQVLTVLRID NTCAPISFDL
     GAAEEQLQTW GIQVPADQYR SLAESALLEP QVRRYIIYNS RPMRLAFAVV FYVVVWANIY
     STSQMFALGN HWAGVLLVTL AATSLTLTLV VIFERHQRKA NTNTDLRLTA ANGALLRHRV
     LLGVTDTVEG CQSVIQLWFV YFDLETCAQF LSDHIREMKM SQESLLRSRL SQLCVVMETG
     VSPTANEGPE NLLEETPLLP DRPGSTEKPL MQTELRQLVP EAEPEEMAQQ LLAVFGGYYT
     RLLVTSQLPQ ALGTRHMDSP RIPCPCQLIE AYILGTECCP FLTR