ID   TM270_BOVIN             Reviewed;         262 AA.
AC   Q2TBQ4;
DT   23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2006, sequence version 1.
DT   25-MAY-2022, entry version 58.
DE   RecName: Full=Transmembrane protein 270 {ECO:0000305};
GN   Name=TMEM270 {ECO:0000250|UniProtKB:Q6UE05};
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; BC109817; AAI09818.1; -; mRNA.
DR   RefSeq; NP_001069914.1; NM_001076446.1.
DR   AlphaFoldDB; Q2TBQ4; -.
DR   STRING; 9913.ENSBTAP00000019713; -.
DR   PaxDb; Q2TBQ4; -.
DR   PRIDE; Q2TBQ4; -.
DR   GeneID; 617180; -.
DR   KEGG; bta:617180; -.
DR   CTD; 135886; -.
DR   eggNOG; ENOG502T0K9; Eukaryota.
DR   InParanoid; Q2TBQ4; -.
DR   OrthoDB; 1511708at2759; -.
DR   Proteomes; UP000009136; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR029166; WBS28.
DR   PANTHER; PTHR37369; PTHR37369; 1.
DR   Pfam; PF15164; WBS28; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..262
FT                   /note="Transmembrane protein 270"
FT                   /id="PRO_0000308414"
FT   TRANSMEM        6..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        30..50
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        67..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        92..112
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        127..147
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          226..262
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        239..262
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   262 AA;  28644 MW;  A6F066A9F3E4DB73 CRC64;
     MEAIPLVRSS LSGTLLVVVK LSALLIQNRA HLYNFLLLKI FLFNHWLLGL TQEAQGFHPP
     SKIAGCPVGR VLWAGLTLLE VPVCLALRVP RLVWAGLLGC ARALGLGPKW LGAWEQLGLS
     AATWTDLFLS CLHSLMLAAL LLLLLVWRLY QKAQCCSLGR LPRKALLQNR VVRRSLALLK
     SLYWWVESTA ALTSWHLAYL ITWTTCLASH LLQAAFEHTA QLAQAQEAEP QKALGLSSET
     PPPGPPAPGA RPVLPEPGTP GE