TM275_MOUSE
ID TM275_MOUSE Reviewed; 177 AA.
AC A0A0U1RQ45;
DT 13-FEB-2019, integrated into UniProtKB/Swiss-Prot.
DT 17-FEB-2016, sequence version 1.
DT 03-AUG-2022, entry version 29.
DE RecName: Full=Transmembrane protein 275 {ECO:0000250|UniProtKB:A0A0U1RQS6};
GN Name=Tmem275 {ECO:0000250|UniProtKB:A0A0U1RQS6};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.;
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Multi-pass membrane
CC protein {ECO:0000255}.
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DR EMBL; AL627085; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CH466552; EDL30630.1; -; Genomic_DNA.
DR CCDS; CCDS89812.1; -.
DR RefSeq; XP_017175991.1; XM_017320502.1.
DR AlphaFoldDB; A0A0U1RQ45; -.
DR ProteomicsDB; 344735; -.
DR Ensembl; ENSMUST00000132221; ENSMUSP00000146242; ENSMUSG00000034185.
DR MGI; MGI:1923487; 6430628N08Rik.
DR VEuPathDB; HostDB:ENSMUSG00000034185; -.
DR GeneTree; ENSGT00390000008086; -.
DR OMA; FFTACCV; -.
DR OrthoDB; 1441529at2759; -.
DR BioGRID-ORCS; 76237; 0 hits in 30 CRISPR screens.
DR PRO; PR:A0A0U1RQ45; -.
DR Proteomes; UP000000589; Chromosome 4.
DR RNAct; A0A0U1RQ45; protein.
DR Bgee; ENSMUSG00000034185; Expressed in superior frontal gyrus and 6 other tissues.
DR ExpressionAtlas; A0A0U1RQ45; baseline and differential.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
PE 3: Inferred from homology;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..177
FT /note="Transmembrane protein 275"
FT /id="PRO_0000446327"
FT TRANSMEM 36..56
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 63..83
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 113..177
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 113..139
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 177 AA; 17701 MW; DC1D17F95C3E11F9 CRC64;
MPQAKKSTET LAPAPPGRSR SLLRSLPSPA LCCACGLCVL LAGLNVTLVG AFAAFLPGHN
VPLVVGPALL VLALGFFAAC CVCSRRGPVP RARSSATAGQ GGGRPGTVAL EMESSERTAQ
DTTAVQLSPA ASAASSGRSS PGPGLFALDP PAPATAAPYL PRTEGTQLNF PRDPAAS