TM2D2_CAEEL
ID TM2D2_CAEEL Reviewed; 195 AA.
AC Q95QZ5;
DT 21-AUG-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 03-AUG-2022, entry version 89.
DE RecName: Full=TM2 domain-containing protein C41D11.9;
DE Flags: Precursor;
GN ORFNames=C41D11.9;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the TM2 family. {ECO:0000305}.
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DR EMBL; FO080509; CCD64258.1; -; Genomic_DNA.
DR RefSeq; NP_491372.1; NM_058971.1.
DR AlphaFoldDB; Q95QZ5; -.
DR STRING; 6239.C41D11.9; -.
DR PaxDb; Q95QZ5; -.
DR EnsemblMetazoa; C41D11.9.1; C41D11.9.1; WBGene00016567.
DR GeneID; 266651; -.
DR KEGG; cel:CELE_C41D11.9; -.
DR UCSC; C41D11.9; c. elegans.
DR CTD; 266651; -.
DR WormBase; C41D11.9; CE29489; WBGene00016567; -.
DR eggNOG; KOG4272; Eukaryota.
DR GeneTree; ENSGT00940000158389; -.
DR HOGENOM; CLU_084872_1_0_1; -.
DR InParanoid; Q95QZ5; -.
DR OMA; QIWRPDR; -.
DR OrthoDB; 1385397at2759; -.
DR PhylomeDB; Q95QZ5; -.
DR PRO; PR:Q95QZ5; -.
DR Proteomes; UP000001940; Chromosome I.
DR Bgee; WBGene00016567; Expressed in embryo and 3 other tissues.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR007829; TM2.
DR Pfam; PF05154; TM2; 1.
PE 3: Inferred from homology;
KW Glycoprotein; Membrane; Reference proteome; Signal; Transmembrane;
KW Transmembrane helix.
FT SIGNAL 1..20
FT /evidence="ECO:0000255"
FT CHAIN 21..195
FT /note="TM2 domain-containing protein C41D11.9"
FT /id="PRO_0000298994"
FT TRANSMEM 137..157
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 164..184
FT /note="Helical"
FT /evidence="ECO:0000255"
FT CARBOHYD 55
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 93
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 127
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 195 AA; 21203 MW; 35945E407F184DAE CRC64;
MLHKILFLIC LASFIPTIGS ISGTKDVKSK NCDGSAGLTC TFPGDCRIGD TVKVNCTSRK
GCPNPVSRNN VEAVCRFCWQ LLPGDYDCEP ATNCSTSSTK LLVTKCSAHS SVICMGQRNF
YKRIPCNWSS GYSWTKTMIL SVVLGGFGAD RFYLGLWKSA IGKLFSFGGL GVWTLVDVVL
IAVGYIKPYD GSMYI