ID   TM2D3_CAEEL             Reviewed;         179 AA.
AC   Q95PJ8;
DT   21-AUG-2007, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2012, sequence version 2.
DT   03-AUG-2022, entry version 93.
DE   RecName: Full=TM2 domain-containing protein Y66D12A.21;
DE   Flags: Precursor;
GN   ORFNames=Y66D12A.21;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TM2 family. {ECO:0000305}.
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DR   EMBL; AL161712; CAC35892.2; -; Genomic_DNA.
DR   RefSeq; NP_499481.2; NM_067080.3.
DR   AlphaFoldDB; Q95PJ8; -.
DR   PaxDb; Q95PJ8; -.
DR   EnsemblMetazoa; Y66D12A.21.1; Y66D12A.21.1; WBGene00013446.
DR   GeneID; 176581; -.
DR   KEGG; cel:CELE_Y66D12A.21; -.
DR   UCSC; Y66D12A.21; c. elegans.
DR   CTD; 176581; -.
DR   WormBase; Y66D12A.21; CE47069; WBGene00013446; -.
DR   eggNOG; KOG4272; Eukaryota.
DR   GeneTree; ENSGT00940000157668; -.
DR   HOGENOM; CLU_110523_1_0_1; -.
DR   InParanoid; Q95PJ8; -.
DR   OMA; VANEINC; -.
DR   OrthoDB; 1467308at2759; -.
DR   PhylomeDB; Q95PJ8; -.
DR   PRO; PR:Q95PJ8; -.
DR   Proteomes; UP000001940; Chromosome III.
DR   Bgee; WBGene00013446; Expressed in germ line (C elegans) and 4 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR007829; TM2.
DR   Pfam; PF05154; TM2; 1.
PE   3: Inferred from homology;
KW   Glycoprotein; Membrane; Reference proteome; Signal; Transmembrane;
KW   Transmembrane helix.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000255"
FT   CHAIN           19..179
FT                   /note="TM2 domain-containing protein Y66D12A.21"
FT                   /id="PRO_0000298995"
FT   TRANSMEM        98..118
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        123..143
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        75
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        169
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   179 AA;  19786 MW;  FEBB1BD2EEB0B35E CRC64;
     MRQLLLTLSL ISVSASDATV KCDDLDPNQY LCKNYAVDTI TQQSVTCAAD NSIQVMCETA
     EHIKCVGKDQ FGIFNRTVPS ACHYGAHVSY TTTVLLSIFL GFFGIDRIYL GYYALGLIKM
     FSLGGLFVFW LVDIILISLQ LLGPADGTAY AMAYYGPKAQ MIRFDSHTNF SFYTCDGCL