ID   TM2D3_DANRE             Reviewed;         244 AA.
AC   A5PLF5;
DT   21-AUG-2007, integrated into UniProtKB/Swiss-Prot.
DT   21-AUG-2007, sequence version 2.
DT   03-AUG-2022, entry version 56.
DE   RecName: Full=TM2 domain-containing protein 3;
DE   Flags: Precursor;
GN   Name=tm2d3; ORFNames=zgc:165591;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Ovary;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TM2 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAI42885.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; BC142884; AAI42885.1; ALT_INIT; mRNA.
DR   RefSeq; NP_001092734.1; NM_001099264.1.
DR   AlphaFoldDB; A5PLF5; -.
DR   STRING; 7955.ENSDARP00000122047; -.
DR   PaxDb; A5PLF5; -.
DR   GeneID; 100093711; -.
DR   KEGG; dre:100093711; -.
DR   CTD; 80213; -.
DR   ZFIN; ZDB-GENE-070620-20; tm2d3.
DR   eggNOG; KOG4272; Eukaryota.
DR   InParanoid; A5PLF5; -.
DR   OrthoDB; 1385397at2759; -.
DR   PRO; PR:A5PLF5; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR007829; TM2.
DR   Pfam; PF05154; TM2; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Membrane; Reference proteome; Signal; Transmembrane;
KW   Transmembrane helix.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255"
FT   CHAIN           22..244
FT                   /note="TM2 domain-containing protein 3"
FT                   /id="PRO_0000298991"
FT   TRANSMEM        177..197
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        213..233
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        86
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        94
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        115
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        137
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        152
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        176
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   244 AA;  26772 MW;  D4324BE9AD823D54 CRC64;
     MSSYIMLVLL LLDIYSSCVD GYLSSPHVGQ DPPYLAQQKS VMSSPVALTA SSASPVVTDN
     YVSKCPSGGL CSKLPADCII CALHHNCSYG RPHNYTCRPR AGVHCVSDQG ERQQNFTLSL
     LCRFCFQLDA SQYRCSNSSD CMTVSCPRRR YNASCEVLEH VHCLGKRVFQ KRLFCNWTGG
     YKWSTALALS ITLGGFGADR FYLGQWREGL GKLFSFGGLG IWTLIDVLLI GVGYVGPADG
     SLYI