ID   TM2D3_XENLA             Reviewed;         247 AA.
AC   Q6DE06;
DT   21-AUG-2007, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 44.
DE   RecName: Full=TM2 domain-containing protein 3;
DE   Flags: Precursor;
GN   Name=tm2d3;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Ovary;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TM2 family. {ECO:0000305}.
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DR   EMBL; BC077341; AAH77341.1; -; mRNA.
DR   RefSeq; NP_001086712.1; NM_001093243.1.
DR   AlphaFoldDB; Q6DE06; -.
DR   DNASU; 446547; -.
DR   GeneID; 446547; -.
DR   KEGG; xla:446547; -.
DR   CTD; 446547; -.
DR   Xenbase; XB-GENE-5805783; tm2d3.S.
DR   OMA; QRYNTTC; -.
DR   OrthoDB; 1385397at2759; -.
DR   Proteomes; UP000186698; Chromosome 2S.
DR   Bgee; 446547; Expressed in ovary and 19 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR007829; TM2.
DR   Pfam; PF05154; TM2; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Membrane; Reference proteome; Signal; Transmembrane;
KW   Transmembrane helix.
FT   SIGNAL          1..30
FT                   /evidence="ECO:0000255"
FT   CHAIN           31..247
FT                   /note="TM2 domain-containing protein 3"
FT                   /id="PRO_0000298992"
FT   TRANSMEM        180..200
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        216..236
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        87
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        99
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        139
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        155
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        169
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        179
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   247 AA;  27513 MW;  130E1E72A98421AE CRC64;
     MDLMMALKRV CRVLLFVTQM YVFSGRGSLS FEYSQPVAQP LKDTFPSSTT ATSIKATTTK
     MPEYMEICPS NGQCSRLASD CMTCATNYSC IYGKLVTFNC TAKNGVVCFD ENSQRQEYFT
     ISMACQFCWQ LPPSDYVCNL SSSCKTISCP RQRYNTTCTV LDHVHCLGNR TFPKMLYCNW
     TGGYKWSTAL ALSITLGGFG ADRFYLGQWR EGLGKLFSFG GLGIWTLIDV FLISVGYVGP
     ADGSLYI